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Proton Pump Inhibition Enhances the Cytotoxicity of Paclitaxel in Cervical Cancer

Song T, Jeon HK, Hong JE, Choi JJ, Kim TJ, Choi CH, Bae DS, Kim BG, Lee JW

PURPOSE: This study was conducted to investigate whether a proton pump inhibitor (PPI) could enhance chemosensitivity via the inhibition of vacuolar-type H⁺ ATPase (V-ATPase) in cervical cancer. MATERIALS AND METHODS: The...
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Expression of Aquaporin-6 in Intercalated Cell subtypes in Rat and Mouse Kidney

Hwang JS, Kim YH, Park EY, Kim WY, Kim J

  • KMID: 2092914
  • Korean J Anat.
  • 2008 Mar;41(1):21-28.
Aquaporin-6 (AQP6) is a water channel protein located in intracellular vesicles of the proximal tubules and in intercalated cells (ICs) in the collecting duct (CD) of the rat kidney. The...
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Regulation of Vacuolar H+-ATPase c Gene Expression by Oxidative Stress

Kwak WJ, Kim SM, Kim MS, Kang JH, Kim DJ, Kim HS, Kown OJ, Kim IK, Jeong SW

  • KMID: 1600110
  • Korean J Physiol Pharmacol.
  • 2005 Oct;9(5):275-282.
By using differential display, we identified one of the genes encoding the multi-subunit complex protein V-ATPase, c subunit gene (ATP6L), and showed alterations of the gene expression by oxidative stresses....
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Refractory Hypertension and Isosexual Pseudoprecocious Puberty Associated with Renin-Secreting Ovarian Steroid Cell Tumor in a Girl

Lee SH, Kang MS, Lee GS, Chung WY

Steroid cell tumor, not otherwise specified (NOS), are rare ovarian tumor, in addition, it is more rare in children. The majority of these tumors produce several steroid hormones, particularly testosterone....
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