- Natural Killer and CD8 T Cells Contribute to Protection by Formalin Inactivated Respiratory Syncytial Virus Vaccination under a CD4-Deficient Condition
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Ko EJ, Lee Y, Lee YT, Hwang HS, Park Y, Kim KH, Kang SM
- KMID: 2511888
- Immune Netw.
- 2020 Dec;20(6):e51.
- doi: 10.4110/in.2020.20.e51
Respiratory syncytial virus (RSV) causes severe pulmonary disease in infants, young children, and the elderly. Formalin inactivated RSV (FI-RSV) vaccine trials failed due to vaccine enhanced respiratory disease, but the... -
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- Respiratory Syncytial Virus Fusion Protein-encoding DNA Vaccine Is Less Effective in Conferring Protection against Inflammatory Disease than a Virus-like Particle Platform
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Kwon YM, Hwang HS, Lee YT, Kim KH, Lee Y, Kim MC, Lee YN, Quan FS, Moore ML, Kang SM
- KMID: 2450203
- Immune Netw.
- 2019 Jun;19(3):e18.
- doi: 10.4110/in.2019.19.e18
Formalin-inactivated respiratory syncytial virus (RSV) vaccination causes vaccine-enhanced disease (VED) after RSV infection. It is considered that vaccine platforms enabling endogenous synthesis of RSV immunogens would induce favorable immune responses... -
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