- Effect of Alpha 1-Adrnoceptor Antagonists on Postsynaptic Sensitivity in Substantia Gelatinosa Neurons From Lumbosacral Spinal Cord in Rats Using Slice Patch-Clamp Technique for mEPSC
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Uta D, Hattori T, Yoshimura M
- KMID: 2503371
- Int Neurourol J.
- 2020 Jun;24(2):135-143.
- doi: 10.5213/inj.1938250.125
Purpose: Alpha1-adrenoceptors participate in improving storage symptoms of male lower urinary tract symptoms (LUTS). However, the mechanism of action of these compounds remains unclear. To clarify the mechanism of the... -
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- Characterization on Responsiveness of Excitatory Synaptic Transmissions to α1-Adrenoceptor Blockers in Substantia Gelatinosa Neurons Isolated From Lumbo-Sacral Level in Rat Spinal Cords
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Uta D, Hattori T, Yoshimura
- KMID: 2446742
- Int Neurourol J.
- 2019 Mar;23(1):13-21.
- doi: 10.5213/inj.1938056.028
PURPOSE: The aim of this study was to characterize the responsiveness of miniature excitatory postsynaptic currents (mEPSCs) to α1-adrenoceptor blockers in substantia gelatinosa (SG) neurons from the spinal cord to... -
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- Differential Effects of Alpha 1-Adrenoceptor Antagonists on the Postsynaptic Sensitivity: Using Slice Patch-Clamp Technique for Inhibitory Postsynaptic Current in Substantia Gelatinosa Neurons From Lumbosacral Spinal Cord in Rats
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Uta D, Hattori T, Yoshimura M
- KMID: 2503370
- Int Neurourol J.
- 2020 Jun;24(2):127-134.
- doi: 10.5213/inj.1938248.124
Purpose: Alpha1-adrenoceptors participate in improving storage symptoms of male lower urinary tract symptoms. However, the mechanism of action of these compounds remains unclear. The goal of the present study was... -
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- Effects of High Concentrations of Naftopidil on Dorsal Root-Evoked Excitatory Synaptic Transmissions in Substantia Gelatinosa Neurons In Vitro
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Uta D, Hattori T, Yoshimura
- KMID: 2431866
- Int Neurourol J.
- 2018 Dec;22(4):252-259.
- doi: 10.5213/inj.1836146.073
PURPOSE: Naftopidil ((±)-1-[4-(2-methoxyphenyl) piperazinyl]-3-(1-naphthyloxy) propan-2-ol) is prescribed in several Asian countries for lower urinary tract symptoms suggestive of benign prostatic hyperplasia. Previous animal experiments showed that intrathecal injection of naftopidil... -
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