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Multi-facets of Corticotropin-releasing Factor in Modulating Inflammation and Angiogenesis

Im E

  • KMID: 2381229
  • J Neurogastroenterol Motil.
  • 2015 Jan;21(1):25-32.
  • doi: 10.5056/jnm14076
The family of corticotropin-releasing factor (CRF) composed of 4 ligands including CRF, urocortin (Ucn) 1, Ucn2, and Ucn3 is expressed both in the central nervous system and the periphery including...
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Corticotropin-releasing Hormone and Its Biological Diversity toward Angiogenesis

Im E

Angiogenesis is the formation of new blood vessels from existing ones and an underlying cause of numerous human diseases, including cancer and inflammation. A large body of evidence indicates that...
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The Effect of Urocortin 1 on Motility in Isolated, Vascularly Perfused Rat Colon

You IY, Lee S, Kim KB, Lee HS, Jang JS, Yeon M, Han JH, Yoon SM, Chae HB, Park SM, Youn SJ

BACKGROUND/AIMS: Urocortin 1, a corticotropin-releasing factor related peptide, increases colonic motility under stressful conditions. We investigated the effect of urocortin 1 on colonic motility using an experimental model with isolated...
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Role of Corticotropin-releasing Factor Signaling in Stress-related Alterations of Colonic Motility and Hyperalgesia

Tache Y, Million M

  • KMID: 2381228
  • J Neurogastroenterol Motil.
  • 2015 Jan;21(1):8-24.
  • doi: 10.5056/jnm14162
The corticotropin-releasing factor (CRF) signaling systems encompass CRF and the structurally related peptide urocortin (Ucn) 1, 2, and 3 along with 2 G-protein coupled receptors, CRF1 and CRF2. CRF binds...
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