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Aberrantly expressed microRNAs in the context of bladder tumorigenesis

Lee JY, Ryu DS, Kim WJ, Kim SJ

MicroRNAs (miRNAs), small noncoding RNAs 19-22 nucleotides in length, play a major role in negative regulation of gene expression at the posttranscriptional level. Several miRNAs act as tumor suppressors or...
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How do we manage high-grade T1 bladder cancer? Conservative or aggressive therapy?

Yun SJ, Kim SK, Kim WJ

High-grade T1 bladder cancer has a poor prognosis due to a higher incidence of recurrence and progression than other nonmuscle invasive bladder cancer; thus patients with high-grade T1 have to...
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High-Grade Hydronephrosis Predicts Poor Outcomes After Radical Cystectomy in Patients with Bladder Cancer

Kim DS, Cho KS, Lee YH, Cho NH, Oh YT, Hong SJ

We examined whether the presence and severity of preoperative hydronephrosis have prognostic significance in patients who underwent radical cystectomy for transitional cell carcinoma of the bladder. The medical records of...
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The role of microRNAs in bladder cancer

Enokida H, Yoshino H, Matsushita R, Nakagawa M

Bladder cancer (BC) is the fifth most common cancer worldwide and is associated with significant morbidity and mortality. The prognosis of muscle invasive BC is poor, and recurrence is common...
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GSTM1 Tissue Genotype as a Recurrence Predictor in Non-muscle Invasive Bladder Cancer

Ha YS, Yan C, Jeong P, Kim WT, Yun SJ, Yi Kim I, Moon SK, Kim WJ

Tissue genotyping is more useful approach than using blood genomic DNA, which can reflect the effects of the somatic mutations in cancer. Although polymorphisms in glutathione S-transferase (GST) have been...
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Endometrial Stromal Sarcoma Presenting as Prevesical Mass Mimicking Urachal Tumor

Jung SI, Shin SS, Choi C, Hwang EC, Kim SO, Kang TW

Endometrial stromal sarcoma (ESS) is a mesenchymal neoplasm that usually occurs as a primary tumor of the uterine corpus, but rarely arises in other sites, such as the ovary, pelvic...
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