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Urodynamic Mechanisms Underlying Overactive Bladder Symptoms in Patients With Parkinson Disease

Vurture G, Peyronnet , Palma JA, Sussman RD, Malacarne , Feigin A, Palmerola , Rosenblum , Frucht S, Kaufmann H, Nitti VW, Brucker BM

PURPOSE: To assess the urodynamic findings in patients with Parkinson disease (PD) with overactive bladder symptoms. METHODS: We performed a retrospective chart review of all PD patients who were seen in...
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Bilateral Ureteral Obstruction Related to Pelvic Rhabdomyosarcoma Presenting with Acute Kidney Injury: A Case Report

Han S, Han KH

Bilateral renal obstruction is a rare critical condition, requiring a prompt diagnostic approach and treatment to restore the renal function. The most commonly observed obstructive uropathy in children is congenital...
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Improvement of Persistent Detrusor Overactivity through Treatment with a Phytotherapeutic Agent (WSY-1075) after Relief of Bladder Outlet Obstruction

Kim SJ, Jeon SH, Kwon EB, Jeong HC, Choi SW, Bae WJ, Cho HJ, Ha US, Hong SH, Lee JY, Hwang SY, Kim SW

PURPOSE: Many patients with benign prostatic hyperplasia need treatment for remaining storage symptoms after surgery. Therefore, we evaluated the effect of the phytotherapeutic agent WSY-1075 on persistent detrusor overactivity (DO)...
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Efficacy of an Alpha-Blocker for the Treatment of Nonneurogenic Voiding Dysfunction in Women: An 8-Week, Randomized, Double-Blind, Placebo-Controlled Trial

Lee YS, Lee KS, Choo MS, Kim JC, Lee JG, Seo JT, Lee JZ, Lee JY, Oh SJ, Na YG

PURPOSE: To evaluate the efficacy of an alpha-1 adrenergic receptor (α1-AR) blocker for the treatment of female voiding dysfunction (FVD) through a pressure-flow study. METHODS: This was a randomized, double-blind, placebo-controlled...
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Outcome of 980 nm diode laser vaporization for benign prostatic hyperplasia: A prospective study

Mithani MH, Khalid SE, Khan SA, Sharif I, Awan AS, Mithani S, Majeed I

PURPOSE: To evaluate the initial experience and outcome of photo-selective vaporization of the prostate (PVP) for benign prostatic hyperplasia (BPH) in Pakistan with the use of a 980 nm diode...
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Development of Decision Support Formulas for the Prediction of Bladder Outlet Obstruction and Prostatic Surgery in Patients With Lower Urinary Tract Symptom/Benign Prostatic Hyperplasia: Part II, External Validation and Usability Testing of a Smartphone App

Choo MS, Jeong SJ, Cho SY, Yoo C, Jeong CW, Ku JH, Oh SJ

PURPOSE: We aimed to externally validate the prediction model we developed for having bladder outlet obstruction (BOO) and requiring prostatic surgery using 2 independent data sets from tertiary referral centers,...
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Development of Decision Support Formulas for the Prediction of Bladder Outlet Obstruction and Prostatic Surgery in Patients With Lower Urinary Tract Symptom/Benign Prostatic Hyperplasia: Part I, Development of the Formula and its Internal Validation

Choo MS, Yoo C, Cho SY, Jeong SJ, Jeong CW, Ku JH, Oh SJ

PURPOSE: As the elderly population increases, a growing number of patients have lower urinary tract symptom (LUTS)/benign prostatic hyperplasia (BPH). The aim of this study was to develop decision support...
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Ketanserin and Naftopidil Enhance the Potentiating Effect of Alpha-Methyl-Serotonin on the Neurally-Induced Contraction of Human Isolated Urinary Bladder Muscle Strips

Hattori T, Lluel P, Rouget C, Rekik M, Yoshiyama

PURPOSE: The aim of this study was to assess the potential involvement of a specific subtype of 5-hydroxytryptamine (5-HT), 5HT(2) receptors in neurally-induced contractions of the human detrusor. METHODS: Contractile responses...
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Near-Normalized Gene Expression Profiles in Bladder With Detrusor Overactivity in Rats With Bladder Outlet Obstruction After Deobstruction

Lee T, Lim US, Kang DH, Jung HD, Kim H, Choi BH, Kang JH, Yoon SM, Park CS

PURPOSE: The pathophysiological role of detrusor overactivity (DO) in the bladder, which is commonly observed in various bladder diseases, is not well understood. DO appears in bladder outlet obstruction (BOO),...
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Pathophysiology of the underactive bladder

Aizawa N, Igawa Y

Underactive bladder (UAB), which has been described as a symptom complex suggestive of detrusor underactivity, is usually characterized by prolonged urination time with or without a sensation of incomplete bladder...
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Clinical implications of underactive bladder

Ko KJ, Lee CU, Lee KS

Underactive bladder (UAB) is a common urologic condition but a complex disease that causes troublesome lower urinary tract symptoms. Currently, management of UAB remains unsatisfactory. Also, many urological diseases can...
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Definition and symptoms of underactive bladder

Uren AD, Drake MJ

Underactive bladder (UAB) is a symptom syndrome reflecting the urodynamic observation of detrusor underactivity (DU), a voiding contraction of reduced strength and/or duration, leading to prolonged or incomplete bladder emptying....
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Thermo-expandable prostatic stents for bladder outlet obstruction in the frail and elderly population: An underutilized procedure?

Sethi K, Bozin M, Jabane T, McMullin R, Cook D, Forsyth R, Dodds L, Putra LJ

PURPOSE: To report our outcomes with the use of a thermo-expandable metallic intraprostatic stent (Memokath) for patients with bladder outlet obstruction (BOO) secondary to prostatic obstruction, and to assess it...
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Urinary Continence after Robot-Assisted Laparoscopic Radical Prostatectomy: The Impact of Intravesical Prostatic Protrusion

Jo JK, Hong SK, Byun SS, Zargar H, Autorino R, Lee SE

PURPOSE: To assess the impact of intravesical prostatic protrusion (IPP) on the outcomes of robot-assisted laparoscopic prostatectomy (RALP). MATERIALS AND METHODS: The medical records of 1094 men who underwent RALP from...
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Development of an Improved Animal Model of Overactive Bladder: Transperineal Ligation versus Transperitoneal Ligation in Male Rats

Kim WH, Bae WJ, Park JW, Choi JB, Kim SJ, Cho HJ, Ha US, Hong SH, Lee JY, Hwang SY, Kim SW

PURPOSE: We compared a transperineal ligation model and a transperitoneal ligation model in male rats to determine which animal model of overactive bladder (OAB) was more useful based on cystometrography,...
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Huge Benign Prostatic Hyperplasia

Byun HJ, Shin TJ, Jung WH, Ha JY, Park CH, Kim CI

Benign prostatic hyperplasia (BPH) is one of the most common diseases in older men and it may be accompanied with significant problems in the quality of life. Histological changes of...
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Does uroflowmetry parameter facilitate discrimination between detrusor underactivity and bladder outlet obstruction?

Lee KS, Song PH, Ko YH

PURPOSE: Though urodynamic study (UDS) is the current established standard to distinguish between detrusor underactivity (DU) and bladder outlet obstruction (BOO), concerns of patient discomfort and potential complications of catheterization...
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Evaluation and Management of Antenatal HydronephrosisEvaluation and Management of Antenatal Hydronephrosis

Hong YK, Lee JH

Antenatal hydronephrosis (ANH) is one of the most common abnormal findings detected on prenatal ultrasound (US), and it has been reported in 1-5% of all pregnancies. The likelihood of significant...
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Role of Nicotinic Acetylcholine Receptor alpha3 and alpha7 Subunits in Detrusor Overactivity Induced by Partial Bladder Outlet Obstruction in Rats

Kim HS, Park WJ, Park EY, Koh JS, Hwang TK, Kim JC

PURPOSE: To investigate the role of alpha3 and alpha7 nicotinic acetylcholine receptor subunits (nAChRs) in the bladder, using a rat model with detrusor overactivity induced by partial bladder outlet obstruction...
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Structural modifications of the prostate in hypoxia, oxidative stress, and chronic ischemia

Thurmond P, Yang JH, Li Y, Lerner LB, Azadzoi KM

PURPOSE: Clinical studies have reported a correlation between pelvic ischemia and voiding dysfunction in elderly men. The aim of this study was to identify and compare prostate structural modifications in...
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