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Association between Neck Circumference and Serum Uric Acid Level in Korean Adults over 40 Years Old: Based on the 2019 Korea National Health and Nutrition Examination Survey

Lee MJ, Hwang HR, Kim YM, Kim KW

Background: Many studies have explored the correlation between waist circumference and risk of hyperuricemia. However, few studies relating neck circumference (NC) with serum uric acid levels exist. This study aimed...
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Detection of Monosodium Urate Crystal of Hand and Wrist in Suspected Gouty Arthritis Patients on DualEnergy CT and Relationship with Serum Urate Level

Choi H, Ryu J, Lee S, Kim YJ, Bang S

Purpose We retrospectively investigated the characteristics of patients with monosodium urate (MSU) deposits of the hand and wrist on dual-energy CT (DECT) compared to those without. We also attempted to determine...
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Growth Factors Upregulated by Uric Acid Affect Guanine Deaminase-Induced Melanogenesis

Kim NH, Lee AY

Uric acid produced by guanine deaminase (GDA) is involved in photoaging and hyperpigmentation. Reactive oxygen species (ROS) generated by uric acid plays a role in photoaging. However, the mechanism by...
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Functional Characterization of Drosophila melanogaster CYP6A8 Fatty Acid Hydroxylase

Lee SA, Kim V, Choi B, Lee H, Chun YJ, Cho KS, Kim D

Genomic analysis indicated that the genome of Drosophila melanogaster contains more than 80 cytochrome P450 genes. To date, the enzymatic activity of these P450s has not been extensively studied. Here,...
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Association between serum uric acid and relative hand grip strength in comparison with metabolic syndrome components

Yi D, Lee MJ, Khang AR, Kang YH

Objectives To investigate the association between serum uric acid (UA) and relative hand grip strength (HGS) in comparison with metabolic syndrome components. Methods We analyzed the data of 5247 Korean adults aged ≥...
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The Association between Serum Uric Acid Levels and the Nutrients Adequacy Ratio among Male Adult Koreans -Based on the 2016∼2019 Korea National Health and Nutrition Examination Survey-

Chae SJ, Lee GS, Kim SH, Ryu HS, Yun ME

This study evaluated the correlation between serum uric acid level and the nutrients adequacy ratio (NAR) using data from the Korea National Health and Nutrition Examination Survey (KNHANES) 2016∼2019. This...
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Association of White Blood Cell Counts, Leukocyte Ratios, and Serum Uric Acid with Clinical Outcome of Intravitreal Bevacizumab in Diabetic Macular Edema

Karimi S, Arabi A, Shahraki T, Safi S

Purpose: To investigate the role of serum uric acid and leukocyte counts and ratios as predictors of clinical outcomes of intravitreal bevacizumab in diabetic macular edema. Methods: In this prospective study,...
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Comparison of Uric Acid Elevation between Aspirin-Ticagrelor and Aspirin-Prasugrel during Dual Antiplatelet Therapy: A Pilot Study

Kang SW, Park SJ, Lee JH, Lee YS, Min MS

Objective: This study evaluated the safety of aspirin-prasugrel (AP) compared to aspirin-ticagrelor (AT) with regards to uric acid (UA) elevation among patients with acute coronary syndrome. Methods: Retrospective analyses of...
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The Association between Serum Uric Acid and Relative Grip Strength: The 7th Korea National Health and Nutrition Examination Survey (2016‒2018)

Seo YB, Yoon YS

Purpose: Uric acid (UA) has both oxidative and antioxidant properties. The relationship between serum UA level and muscle strength is unclear. We aimed to investigate the relationship between serum UA...
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Distinct Gut Microbiota in Patients with Asymptomatic Hyperuricemia: A Potential Protector against Gout Development

Kim HW, Yoon EJ, Jeong SH, Park MC

Purpose: Here, we aimed to elucidate the differences in microbiota composition between patients with gout and those with asymptomatic hyperuricemia (asHU) and determine the effect of uric acid-lowering therapy (ULT)...
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Association of Serum Uric Acid with Glycemic Control in Patients with Diabetes Mellitus: Analysis of the 2016–2018 Korea National Health and Nutrition Examination Survey

Park S, Nam GE, Huh Y, Park GH, Park CM, Kim W, Kim YH, Cho KH

Background: Previous studies have reported the association between serum uric acid levels and diabetes mellitus. This study aimed to investigate the association between serum uric acid levels and glycemic control...
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Validation of age- and sex-dependent association of uric acid and incident hypertension in rural areas

Kim IJ, Kim W, Go TH, Kang DR, Kim JY, Kim EJ

Background: A previous study based on urban areas suggested the age- and sex-dependent association of uric acid (UA) and incident hypertension. We aimed to investigate whether this association is valid...
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Spot Urine Uric Acid to Creatinine Ratio used in the Estimation of Hyperuricosuria in the Young Korean Population

Choi H, Namgoong M

Background: Uric acid levels in urine are measured using urine specimens 24 hours or by uric acid glomerular filtration rate (UAGFR) with spot urine, which additionally requires a blood sample....
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Association of Sleep Duration with Serum Uric Acid Levels in Korean Adults: An Analysis of the 2016–2018 Korea National Health and Nutrition Examination Survey Data

Chung S, Nam GE, Huh Y, Seo S, Park CM, Kim W, Kim YH, Cho KH

Background: Recent studies have suggested that both sleep duration and serum uric acid levels may be important risk factors for many chronic diseases. However, there have been only a few...
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Fructose in the kidney: from physiology to pathology

Nakagawa T, Kang DH

The Warburg effect is a unique property of cancer cells, in which glycolysis is activated instead of mitochondrial respiration despite oxygen availability. However, recent studies found that the Warburg effect...
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J-shaped Relationship Between Chronic Kidney Disease and Serum Uric Acid Levels: A Cross-sectional Study on the Korean Population

Koo BS, Jeong HJ, Son CN, Kim SH, Kim GH, Jun JB

Objective Both hypouricemia and hyperuricemia are reportedly associated with reduced kidney function. This study investigated the association between uric acid levels and the risk of reduced renal function in men...
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β-Patchoulene: Conversion from Patchouli Alcohol by Acid Catalysts and its In silico Anti-inflammatory Study

F, Soekamto NH, Firdausiah S, Rasyid H, Rifai A

β-patchoulene (β-PAE) is a tricyclic sesquiterpene which performed many potential bioactivities and can be found in patchouli oil but in very low concentration. This study aimed to obtained β-PAE in...
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Association between Albumin, Total Bilirubin, and Uric Acid Serum Levels and the Risk of Cancer: A Prospective Study in a Korean Population

Kim YR, Choi CK, Lee YH, Choi SW, Kim HY, Shin MH, Kweon SS

Purpose: In this prospective study, we evaluated the association between the serum levels of antioxidants uric acid (UA), albumin, and total bilirubin and the risk of cancer in a Korean...
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Urate Transporters in the Kidney: What Clinicians Need to Know

Chung S, Kim GH

Urate is produced in the liver by the degradation of purines from the diet and nucleotide turnover and excreted by the kidney and gut. The kidney is the major route...
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Uric acid albumin ratio as a predictive marker of short-term mortality in patients with acute kidney injury

Özgür Y, Akın S, Yılmaz NG, Gücün M, Keskin

Objective We aimed to investigate uric acid and albumin ratio (UA/A) as a marker of short-term mortality in acute kidney injury (AKI). Both uric acid and albumin are strongly correlated...
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