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Comparison of intraoperative and short-term postoperative outcomes between robot-assisted laparoscopic multi-port pyeloplasty using the da Vinci Si system and single-port pyeloplasty using the da Vinci SP system in children

Kang SK, Jang WS, Kim SH, Kim SW, Han SW, Lee YS

Purpose: We compared the intraoperative and postoperative outcomes of single-port robot-assisted laparoscopic pyeloplasty (SRALP) using the da Vinci SP® system and conventional multi-port robot-assisted laparoscopic pyeloplasty (M-RALP) in pediatric patients. Materials...
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IDH2 gene deficiency accelerates unilateral ureteral obstructioninduced kidney inflammation through oxidative stress and activation of macrophages

Kim JI, Noh MR, Yoon GE, Jang HS, Kong MJ, Park KM

Mitochondrial NADP+-dependent isocitrate dehydrogenase 2 (IDH2) produces NADPH, which is known to inhibit mitochondrial oxidative stress. Ureteral obstruction induces kidney inflammation and fibrosis via oxidative stress. Here, we investigated the...
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L-carnitine treatment attenuates renal tubulointerstitial fibrosis induced by unilateral ureteral obstruction

Zhao HY, Li HY, Jin J, Jin JZ, Zhang LY, Xuan MY, Jin XM, Jiang YJ, Zheng HL, Jin YS, Jin YJ, Choi BS, Yang CW, Piao SG, Li C

Background/Aims: Accumulating evidence indicates that L-carnitine (LC) protects against multiorgan damage through its antioxidant properties and preservation of the mitochondria. Little information is available about the effects of LC on...
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KF-1607, a Novel Pan Src Kinase Inhibitor, Attenuates Obstruction-Induced Tubulointerstitial Fibrosis in Mice

Dorotea D, Lee S, Lee SJ, Lee G, Son JB, Choi HG, Ahn SM, Ha H

Src family kinases (SFKs), an important group of non-receptor tyrosine kinases, are suggested to be excessively activated during various types of tissue fibrosis. The present study investigated the effect of...
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Role of Chemical Exchange Saturation Transfer andMagnetization Transfer MRI in Detecting Metabolicand Structural Changes of Renal Fibrosis in an AnimalModel at 3T

Li A, Xu C, Liang P, Hu Y, Shen Y, Hu D, Li Z, Kamel IR

Objective: To investigate the value of combined chemical exchange saturation transfer (CEST) and conventional magnetization transfer imaging (MT) in detecting metabolic and structural changes of renal fibrosis in rats with unilateral...
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Robot-assisted distal ureteral reconstruction for benign pathology: Current state

Asghar AM, Lee RA, Yang KK, Metro M, Eun DD

Distal ureteral reconstruction for benign pathologies such as stricture disease or iatrogenic injury has posed a challenge for urologist as endoscopic procedures have poor long-term outcomes, requiring definitive open reconstruction....
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Recent Advances in Ureteral Stents

Park C, Shin JH

A ureteral stent is widely used to drain ureteral obstructions, which allows urine to bypass the obstruction. The double J stent, a representative ureteral stent, has undergone many advancements in...
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Pure single-site robot-assisted pyeloplasty with the da Vinci SP surgical system: Initial experience

Heo JE, Kang SK, Koh DH, Na JC, Lee YS, Han WK, Choi YD, Jang WS

PURPOSE: Laparoendoscopic single-site surgery (LESS) reduces the limited invasiveness of conventional laparoscopy while providing superior cosmetic results. However, LESS remains a challenging surgical technique, even in robotic surgery, primarily due...
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Transperitoneal laparoscopic ureteroureterostomy with excision of the compressed ureter for retrocaval ureter and review of literature

Seo IY, Oh TH, Jeon SH

PURPOSE: We present surgical techniques and operative results of laparoscopic reconstruction for patients with retrocaval ureter (RCU) and review similar papers. MATERIALS AND METHODS: Ten patients with RCU were enrolled in...
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Is Double J Stenting or Percutaneous Nephrostomy More Suitable for Maximizing the Clinical Effects of Temporary Urinary Diversion for Acute Pyelonephritis with a Complicated Ureteral Stone?

Choi J, Choi T, Lee DG, Min GE, Lee HL, Yoo KH

PURPOSE: This study compared the clinical benefits of double J (DJ) ureteral stenting with percutaneous nephrostomy (PCN) for the management of acute pyelonephritis (APN) with complicated ureteral stones. MATERIALS AND METHODS:...
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Notch signaling in the collecting duct regulates renal tubulointerstitial fibrosis induced by unilateral ureteral obstruction in mice

Choi A, Nam SA, Kim WY, Park SH, Kim H, Yang CW, Kim J, Kim YK

BACKGROUND/AIMS: Mind bomb-1 (Mib1) encodes an E3 ubiquitin ligase, which is required for the initiation of Notch signaling. Recently, it was demonstrated that the renal collecting duct plays an important...
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Effects of colchicine on renal fibrosis and apoptosis in obstructed kidneys

Kim S, Jung ES, Lee J, Heo NJ, Na KY, Han JS

BACKGROUND/AIMS: Colchicine is an established drug for microtubule stabilization that may reduce tissue injury. No data were available that its effects may depend on the dosage of colchicine. We investigated...
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A Case of an Ureteropelvic Junction Obstruction Caused by a Crossing Vessel

Kim MY, Im YJ, Hyun HS, Kang HG, Ha IS, Cheong HI, Park E

Ureteropelvic junction obstruction is one of the common causes of hydronephrosis in infancy and childhood. Most cases of ureteropelvic junction obstruction are diagnosed prenatally and are usually asymptomatic. Although less...
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Renal function is associated with prognosis in stent-change therapy for malignant ureteral obstruction

Yoon JH, Park S, Park S, Moon KH, Cheon SH, Kwon T

PURPOSE: The authors performed this study to investigate the risk factors for predicting stent failure and to evaluate its impact on prognosis. MATERIALS AND METHODS: Between January 2002 and March 2017,...
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Evaluation of the ureteral jet in dogs by using color Doppler ultrasonography

Oh H, Kim S, Kim S, Lee J, Yun S, Yoon J, Jung J, Choi M

Ureteral jets are the result of a forceful ejection of urine from the vesicoureteral junction into the urinary bladder. By using color Doppler ultrasonography (US), we aimed to identify distinct...
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Retroperitoneal fibrosis-clinical presentation and outcome analysis from urological perspective

Jadhav KK, Kumar V, Punatar CB, Joshi VS, Sagade SN

PURPOSE: To study clinical presentation, laboratory results, imaging findings and treatment options and outcomes of retroperitoneal fibrosis (RPF). To determine whether it follows the same natural course and response to...
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Lobeglitazone, a Novel Peroxisome Proliferator-Activated Receptor γ Agonist, Attenuates Renal Fibrosis Caused by Unilateral Ureteral Obstruction in Mice

Bae KH, Seo JB, Jung YA, Seo HY, Kang SH, Jeon HJ, Lee JM, Lee S, Kim JG, Lee IK, Jung GS, Park KG

BACKGROUND: Renal tubulointerstitial fibrosis is a common feature of the final stage of nearly all cause types of chronic kidney disease. Although classic peroxisome proliferator-activated receptor γ (PPARγ) agonists have...
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Altered Nitric Oxide System in Cardiovascular and Renal Diseases

Lee J, Bae EH, Ma SK, Kim SW

Nitric oxide (NO) is synthesized by a family of NO synthases (NOS), including neuronal, inducible, and endothelial NOS (n/i/eNOS). NO-mediated effects can be beneficial or harmful depending on the specific...
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What Are the Predictive Factors of Severe Conditions in Acute Obstructive Pyelonephritis?

Kamei J, Homma Y

Acute obstructive pyelonephritis is a common urological infection, often requiring emergency drainage, which shows rapid progression to serious conditions, including severe sepsis or septic shock. Therefore, during an initial evaluation,...
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Concomitant inhibition of renin angiotensin system and Toll-like receptor 2 attenuates renal injury in unilateral ureteral obstructed mice

Chung S, Jeong JY, Chang YK, Choi DE, Na KR, Lim BJ, Lee KW

BACKGROUND/AIMS: There has been controversy about the role of Toll-like receptor 2 (TLR2) in renal injury following ureteric obstruction. Although inhibition of the renin angiotensin system (RAS) reduces TLR2 expression...
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