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Isolation of MLL1 Inhibitory RNA Aptamers

Ul-Haq A, Jin ML, Jeong KW, Kim HM, Chun KH

Mixed lineage leukemia proteins (MLL) are the key histone lysine methyltransferases that regulate expression of diverse genes. Aberrant activation of MLL promotes leukemia as well as solid tumors in humans,...
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Human Organic Anion Transporting Polypeptide 1B3 Applied as an MRI-Based Reporter Gene

Baek SE, Ul-Haq A, Kim DH, Choi HW, Kim MJ, Choi HJ, Kim H

Objective: Recent innovations in biology are boosting gene and cell therapy, but monitoring the response to these treatments is difficult. The purpose of this study was to find an MRI-reporter...
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