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Fyn Kinase: A Potential Therapeutic Target in Acute Kidney Injury

Uddin MJ, Dorotea D, Pak ES, Ha H

Acute kidney injury (AKI) is a common disease with a complex pathophysiology which significantly contributes to the development of chronic kidney disease and end stage kidney failure. Preventing AKI can...
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Kidney protective potential of lactoferrin: pharmacological insights and therapeutic advances

Zahan MS, Ahmed KA, Moni A, Sinopoli A, Ha H, Uddin MJ

Kidney disease is becoming a global public health issue. Acute kidney injury (AKI) and chronic kidney disease (CKD) have serious adverse health outcomes. However, there is no effective therapy to treat...
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Carbon monoxide releasing molecule-2 protects mice against acute kidney injury through inhibition of ER stress

Uddin MJ, Pak ES, Ha H

Acute kidney injury (AKI), which is defined as a rapid decline of renal function, becomes common and recently recognized to be closely intertwined with chronic kidney diseases. Current treatment for...
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Peroxisomal Fitness: A Potential Protective Mechanism of Fenofibrate against High Fat Diet-Induced Non-Alcoholic Fatty Liver Disease in Mice

Jiang S, Uddin MJ, Yu X, Piao L, Dorotea D, Oh GT, Ha H

Background: Non-alcoholic fatty liver disease (NAFLD) has been increasing in association with the epidemic of obesity and diabetes. Peroxisomes are single membrane-enclosed organelles that play a role in the metabolism...
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