- The Macrophage-Specific Transcription Factor Can Be Modified Posttranslationally by Ubiquitination in the Lipopolysaccharide-Treated Macrophages
-
Jung JW, Choi JC, Kim JY, Park IW, Choi BW, Shin JW, Christman
- KMID: 1442860
- Tuberc Respir Dis.
- 2011 Feb;70(2):113-124.
- doi: 10.4046/trd.2011.70.2.113
BACKGROUND: Macrophages are one of the most important inflammatory cells in innate immunity. PU.1 is a macrophage-specific transcription factor. Ubiquitins are the ultimate regulator of eukaryotic transcription. The ubiquitination process... -
- CITED
-
- Close
- SHARE
-
- Close
- Effects of a Proteasome Inhibitor on Cardiomyocytes in a Pressure-Overload Hypertrophy Rat Model: An Animal Study
-
Kim IS, Jo WM
- KMID: 2381896
- Korean J Thorac Cardiovasc Surg.
- 2017 Jun;50(3):144-152.
- doi: 10.5090/kjtcs.2017.50.3.144
BACKGROUND: The ubiquitin-proteasome system (UPS) is an important pathway of proteolysis in pathologic hypertrophic cardiomyocytes. We hypothesize that MG132, a proteasome inhibitor, might prevent hypertrophic cardiomyopathy (CMP) by blocking the... -
- CITED
-
- Close
- SHARE
-
- Close
