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Chemokine and Chemokine Receptor Polymorphisms in Bipolar Disorder

Tokac D, Tuzun E, Gulec H, Yılmaz V, Bireller E, Cakmakoglu B, Kucukali C

OBJECTIVE: Bipolar disorder (BD) is a debilitating psychiatric disease with unknown etiology. Recent studies have shown inflammation as a potential contributing factor of BD pathogenesis. However, potential associations between chemokine...
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NLRP1-Mediated Antidepressant Effect of Ketamine in ChronicUnpredictable Mild Stress Model in Rats

Aricioğlu F, Yalcinkaya C, Ozkartal C, Tuzun E, Sirvanci S, Kucukali C, Utkan T

Objective NOD-like receptor protein 1 (NLRP1) inflammasome complex has been recently associated with chronic unpredictable mild stress (CUMS) model of depression. Our aim was to investigate whether ketamine-induced antidepressant effect is...
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