- Clinical Course of Hepatitis B Viral Infection in Patients Undergoing Anti-Tumor Necrosis Factor α Therapy for Inflammatory Bowel Disease
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Lee JM, Wei SC, Lee KM, Ye BD, Mao R, Kim HS, Park SJ, Park SH, Oh EH, Im JP, Jang BI, Kim DB, Takeuchi K
- KMID: 2529846
- Gut Liver.
- 2022 May;16(3):396-403.
- doi: 10.5009/gnl210081
Background/Aims: Little is known about the clinical course of hepatitis B virus (HBV)-infected patients undergoing anti-tumor necrosis factor α (TNF-α) therapy for inflammatory bowel disease (IBD). We aimed to investigate... -
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- Galectin-3 inhibits cardiac contractility via a tumor necrosis factor alpha-dependent mechanism in cirrhotic rats
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Yoon KT, Liu H, Zhang J, Han S, Lee SS
- KMID: 2528252
- Clin Mol Hepatol.
- 2022 Apr;28(2):232-241.
- doi: 10.3350/cmh.2021.0141
Background/Aims: Galectin-3 plays a key pathogenic role in cardiac hypertrophy and heart failure. The present study aimed to investigate the effects of galectin-3 on cardiomyopathy – related factors and cardiac... -
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- Influence of anti-tumor necrosis factor-alpha therapy to pregnant inflammatory bowel disease women and their children's immunity
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Lee KE, Jung SA, Park SH, Moon CM, Shim SY, Kim ES, Cho SJ, Kim SE, Cho KB, Yang SK
- KMID: 2449965
- Intest Res.
- 2019 Apr;17(2):237-243.
- doi: 10.5217/ir.2018.00071
BACKGROUND/AIMS: The onset of inflammatory bowel disease (IBD) usually occurs at young age, and therefore, women IBD patients experience pregnancy during their disease progression. Recently, the use of anti-tumor necrosis... -
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- Anti-Tumor Necrosis Factor Therapy in Intestinal Behçet's Disease
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Park J, Cheon JH
- KMID: 2427452
- Gut Liver.
- 2018 Nov;12(6):623-632.
- doi: 10.5009/gnl17462
Intestinal Behçet's disease is a rare, immune-mediated chronic intestinal inflammatory disease; therefore, clinical trials to optimize the management and treatment of patients are scarce. Moreover, intestinal Behçet's disease is difficult... -
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- IgA nephropathy in a patient with ankylosing spondylitis well controlled with etanercept
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Lee DH, Kim GT, Hwang NK, Kim EH
- KMID: 2415843
- Kosin Med J.
- 2018 Jun;33(1):85-90.
- doi: 10.7180/kmj.2018.33.1.85
Ankylosing spondylitis (AS) can involve the eye, gastrointestinal system, cardiopulmonary system, skin, kidneys, and spinal and peripheral joints. It is rarely accompanied by immunoglobulin A (IgA) nephropathy. Although IgA is... -
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- A Case of Essential Thrombocythemia in a Patient with Ankylosing Spondylitis Concomitantly Treated with Adalimumab
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Lee DS, Lee SG, Shin HJ, Lee SH, Park EK, Na HJ, Park CH, Park JH, Han IS, Kim GT
- KMID: 2222928
- J Rheum Dis.
- 2015 Feb;22(1):51-55.
- doi: 10.4078/jrd.2015.22.1.51
Extreme thrombocytosis in patients with ankylosing spondylitis (AS) is rarely reported. Because the relationship between high disease activity and increased platelet counts is somewhat contradictory, severe thrombocytosis in AS patients... -
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- Effects of Tumor Necrosis Factor Alpha Blocker Adalimumab in Experimental Spinal Cord Injury
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Borcek AO, Civi S, Ocal O, Gulbahar O
- KMID: 2191185
- J Korean Neurosurg Soc.
- 2015 Feb;57(2):73-76.
- doi: 10.3340/jkns.2015.57.2.73
OBJECTIVE: Tumor necrosis factor alpha (TNF-alpha) have proven effects in pathogenesis of neuroinflammation after spinal cord injury (SCI). Current study is designed to evaluate the effects of an anti-TNF-alpha agent,... -
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- Diagnosis and Treatment of Ulcerative Colitis with Cytomegalovirus Infection: Importance of Controlling Mucosal Inflammation to Prevent Cytomegalovirus Reactivation
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Nakase H, Honzawa Y, Toyonaga T, Yamada S, Minami N, Yoshino T, Matsuura M
- KMID: 2174332
- Intest Res.
- 2014 Jan;12(1):5-11.
- doi: 10.5217/ir.2014.12.1.5
Human cytomegalovirus (HCMV) is a member of the herpesvirus family. HCMV infection persists throughout the host lifespan in a latent state following primary infection. The ability of HCMV to escape... -
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- Effects of Diet-Induced Mild Obesity on Airway Hyperreactivity and Lung Inflammation in Mice
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Jung SH, Kwon JM, Shim JW, Kim DS, Jung HL, Park MS, Park SH, Lee J, Lee WY, Shim JY
- KMID: 1798140
- Yonsei Med J.
- 2013 Nov;54(6):1430-1437.
- doi: 10.3349/ymj.2013.54.6.1430
PURPOSE: Obesity has been suggested to be linked to asthma. However, it is not yet known whether obesity directly leads to airway hyperreactivity (AHR) or obesity-induced airway inflammation associated with... -
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- Biological Therapy for the Prevention and Treatment of Postoperative Endoscopic Recurrence in Crohn's Disease: Time for Acceptance?
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Kotze PG, Saad-Hossne R
- KMID: 2284912
- Intest Res.
- 2013 Oct;11(4):256-260.
- doi: 10.5217/ir.2013.11.4.256
In most patients, postoperative endoscopic recurrence (PER) occurs 1 year after abdominal resection for Crohn's disease (CD). Preventing PER is essential for disease control, as most patients develop further clinical... -
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- Cilostazol Decreases Ethanol-Mediated TNFalpha Expression in RAW264.7 Murine Macrophage and in Liver from Binge Drinking Mice
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Lee YJ, Eun JR
- KMID: 2071759
- Korean J Physiol Pharmacol.
- 2012 Apr;16(2):131-138.
- doi: 10.4196/kjpp.2012.16.2.131
Alcoholic hepatitis is a leading cause of liver failure in which the increased production of tumor necrosis factor alpha (TNFalpha) plays a critical role in progression of alcoholic liver disease.... -
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- Tumor Necrosis Factor-alpha and Apoptosis Following Spinal Nerve Ligation Injury in Rats
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Kim SH, Nam JS, Choi DK, Koh WW, Suh JH, Song JG, Shin JW, Leem JG
- KMID: 2074012
- Korean J Pain.
- 2011 Dec;24(4):185-190.
- doi: 10.3344/kjp.2011.24.4.185
BACKGROUND: Spinal nerve ligation (SNL) injury in rats produces a pain syndrome that includes mechanical and thermal allodynia. Previous studies have indicated that proinflammatory cytokines such as tumor necrosis factor-alpha... -
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- Comparing Scalpel, Electrocautery and Ultrasonic Dissector Effects: The Impact on Wound Complications and Pro-Inflammatory Cytokine Levels in Wound Fluid from Mastectomy Patients
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Yilmaz KB, Dogan L, Nalbant H, Akinci M, Karaman N, Ozaslan C, Kulacoglu
- KMID: 2175644
- J Breast Cancer.
- 2011 Mar;14(1):58-63.
- doi: 10.4048/jbc.2011.14.1.58
PURPOSE: Introducing the relationship between the surgical instruments used in modified radical mastectomy and wound complications is important for preventing and decreasing complications. This prospective randomized trial was designed to... -
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- Measurement of Inflammatory Cytokines in Patients with Rheumatoid Arthritis
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Kang SY, Kim MH, Lee WI
- KMID: 1781631
- Korean J Lab Med.
- 2010 Jun;30(3):301-306.
- doi: 10.3343/kjlm.2010.30.3.301
BACKGROUND: Inflammatory cytokines such as tumor necrosis factor alpha (TNFalpha) and interleukin (IL)-6 play an important role in pathophysiology of rheumatoid arthritis (RA). We investigated the possibility whether TNFalpha and... -
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- A Case of Treatment with Etanercept in Rheumatoid Arthritis Patient on Hemodialysis
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Baek DH, Song EJ, Lee MH, Lee SR, Sung SA, Hwang YH, Hur JW
- KMID: 1270162
- J Korean Rheum Assoc.
- 2008 Dec;15(4):317-321.
- doi: 10.4078/jkra.2008.15.4.317
Disease-modifying antirheumatic drugs (DMARDs) have been used for rheumatoid arthritis (RA) with the aim of controlling synovitis and reducing radiologic progression. Although methotrexate (MTX) is one of the most effective... -
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- Rutin inhibits osteoclast formation by decreasing reactive oxygen species and TNF-alpha by inhibiting activation of NF-kappaB
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Kyung TW, Lee JE, Shin HH, Choi HS
- KMID: 1103588
- Exp Mol Med.
- 2008 Feb;40(1):52-58.
- doi: 10.3858/emm.2008.40.1.52
Rutin, a glycoside of flavonol, inhibits osteoclast formation induced by receptor activator of NF-kappaB ligand (RANKL) in bone marrow-derived macrophages. It reduces reactive oxygen species produced by RANKL and its... -
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- TNF-alpha and IL-12 Secretion in Macrophages in Response to Spores of Bacillus anthracis Sterne
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Baek JJ, Jung KH, Chai YG
- KMID: 2055021
- J Bacteriol Virol.
- 2006 Sep;36(3):141-150.
- doi: 10.4167/jbv.2006.36.3.141
Baerobic, spore forming, and rod-shaped bacterium. Anthrax spores are introduced into macrophage by phagocytosis and multiply after germination. The anthrax spores infected in macrophage produce lethal toxin eventually caused cell... -
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- Role of Tumor Necrosis Factor Alpha, Interleukin 8 and Dexamethasone in the FAK Expression by Human Nucleus Pulposus Cells
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Yoon JH, Lee JH
- KMID: 1575167
- J Korean Orthop Res Soc.
- 2006 Apr;9(1):40-47.
PURPOSE: Human nucleus pulposus cells from intervertebral disc specimens were cultured to study the effects of TNF-alphaand IL-8 on the FAK expression by these cells. The effect of co-stimulation with... -
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- Effect of Histone H1 on Collagen Induced Arthritis in Mice
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Yang JH, Shin KM, Kim DS
- KMID: 2037362
- Korean J Pediatr.
- 2004 Jul;47(7):779-788.
OBJECTIVE: Besides the functions of histones in the nucleus of the cells, there is growing evidence that histones have many other extra-cellular or extra-nuclear functions, such as stabilizing axonemal microtubule... -
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- Recent Advances in the Treatment of Spondyloarthropathy
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Yoo DH
- KMID: 2183130
- J Korean Med Assoc.
- 2003 Nov;46(11):972-980.
- doi: 10.5124/jkma.2003.46.11.972
Spondyloarthropathy is a chronic inflammatory disease involving axial joints and peripheral joints, and finally induces ankylosis of the spine. Treatment of spondyloarthropathy including ankylosing spondylitis has many limitations. Nonsteroidal anti-inflammatory... -
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