- Production of tumor necrosis factor-alpha by alveolar macrophages from patients with pulmonary tuberculosis
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Kim SJ, Kim HI, Lee YH, Kim SK
- KMID: 1421514
- J Korean Med Sci.
- 1991 Mar;6(1):45-53.
- doi: 10.3346/jkms.1991.6.1.45
In order to ascertain the role of TNF-alpha in pulmonary tuberculosis, we determined the TNF-alpha productivity of alveolar macrophages(AMs) obtained by bronchoalveolar lavage(BAL), along with the level of TNF-alpha in... -
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- Expression of TNF-alpha and TGF-beta1 in the Rat Brain After a Single High-Dose Irradiation
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Kim SH, Lim DJ, Chung YG, Cho TH, Lim SJ, Kim WJ, Suh JK
- KMID: 648684
- J Korean Med Sci.
- 2002 Apr;17(2):242-248.
- doi: 10.3346/jkms.2002.17.2.242
Cytokines and growth factors are important regulatory proteins controlling the growth and differentiation of normal and malignant glial cells. In this study, we investigated the expression and origin of tumor... -
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- Chemical inhibitors destabilize HuR binding to the AU-rich element of TNF-alpha mRNA
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Chae MJ, Sung HY, Kim EH, Lee M, Kwak H, Chae CH, Kim S, Park WY
- KMID: 1122283
- Exp Mol Med.
- 2009 Nov;41(11):824-831.
- doi: 10.3858/emm.2009.41.11.088
Hu protein R (HuR) binds to the AU-rich element (ARE) in the 3'UTR to stabilize TNF-alpha mRNA. Here, we identified chemical inhibitors of the interaction between HuR and the ARE... -
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- Grifola frondosa water extract alleviates intestinal inflammation by suppressing TNF-alpha production and its signaling
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Lee JS, Park SY, Thapa D, Choi MK, Chung IM, Park YJ, Yong CS, Choi HG, Kim JA
- KMID: 983987
- Exp Mol Med.
- 2010 Feb;42(2):143-154.
- doi: 10.3858/emm.2010.42.2.016
TNF-alpha is a major cytokine involved in inflammatory bowel disease (IBD). In this study, water extract of Grifola frondosa (GFW) was evaluated for its protective effects against colon inflammation through... -
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- Signaling pathway for 2,3,7,8-tetrachlorodibenzo- p-dioxin-induced TNF-alpha production in differentiated THP-1 human macrophages
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Cheon HJ, Woo YS, Lee JY, Kim HS, Kim HJ, Cho S, Won NH, Sohn J
- KMID: 756076
- Exp Mol Med.
- 2007 Aug;39(4):524-534.
2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD), a prototypic halogenated aromatic hydrocarbon (HAH), is known as one of the most potent toxicants. At least a part of its toxic effects appears to be derived from... -
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