- Ribonucleotide Reductase Subunit M2 Can Be New Molecular Target and Prognostic Biomarker of Hepatocellular Carcinoma
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Kim HY, Kim CW
- KMID: 2070072
- Gut Liver.
- 2014 Nov;8(6):580-581.
- doi: 10.5009/gnl14377
No abstract available. -
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- Prognostic impact of epithelial cell adhesion molecule in ovarian cancer patients
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Lee M
- KMID: 2130126
- J Gynecol Oncol.
- 2014 Oct;25(4):352-354.
- doi: 10.3802/jgo.2014.25.4.352
No abstract available. -
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- Expression of Glycolysis-Related Proteins in Solid Papillary Carcinoma of the Breast According to Basement Membrane Status
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Kwon JE, Jung WH, Koo JS
- KMID: 2068665
- Yonsei Med J.
- 2014 May;55(3):576-583.
- doi: 10.3349/ymj.2014.55.3.576
PURPOSE: The aim of this study was to investigate the differences of expression in glycolysis-related proteins such as Glut-1, carbonic anhydrase (CA) IX, and monocarboxylate transporter (MCT) 4 according to... -
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- Intracranial immature teratoma with syncytiotrophoblasts and tumor marker positive intestinal lining cells
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Go JH, Bae JY, Kim TS
- KMID: 699866
- Yonsei Med J.
- 1995 Dec;36(6):534-537.
- doi: 10.3349/ymj.1995.36.6.534
Intracranial teratomas are rare entities that can present as a pure type or as mixed germ cell tumor. Cases of mixed germ cell tumor composed of immature teratoma and choriocarcinoma... -
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- Prognostic Significance of p53, mTOR, c-Met, IGF-1R, and HSP70 Overexpression after the Resection of Hepatocellular Carcinoma
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Kang GH, Lee BS, Lee ES, Kim SH, Lee HY, Kang DY
- KMID: 1774532
- Gut Liver.
- 2014 Jan;8(1):79-87.
BACKGROUND/AIMS: The current study examines the expression of molecular biomarkers in hepatocellular carcinoma (HCC) and whether these findings correlate with the clinicopathologic features of the disease and patient survival. METHODS: We... -
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- High Expression of Ribonucleotide Reductase Subunit M2 Correlates with Poor Prognosis of Hepatocellular Carcinoma
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Lee B, Ha SY, Song DH, Lee HW, Cho SY, Park CK
- KMID: 2070085
- Gut Liver.
- 2014 Nov;8(6):662-668.
- doi: 10.5009/gnl13392
BACKGROUND/AIMS: Ribonucleotide reductase subunit M2 (RRM2) catalyzes the production of deoxynucleotide triphosphates, which are necessary for DNA synthesis. RRM2 has been reported to play an active role in tumor progression,... -
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- DNA mismatch repair-related protein loss as a prognostic factor in endometrial cancers
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Kato M, Takano M, Miyamoto M, Sasaki N, Goto T, Tsuda H, Furuya K
- KMID: 2158801
- J Gynecol Oncol.
- 2015 Jan;26(1):40-45.
- doi: 10.3802/jgo.2015.26.1.40
OBJECTIVE: Recent investigations have revealed DNA mismatch repair (MMR) gene mutations are closely related with carcinogenesis of endometrial cancer; however the impact of MMR protein expression on prognosis is not... -
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- Immunoexpression of HBME-1, High Molecular Weight Cytokeratin, Cytokeratin 19, Thyroid Transcription Factor-1, and E-cadherin in Thyroid Carcinomas
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Choi YL, Kim MK, Suh JW, Han J, Kim JH, Yang JH, Nam SJ
- KMID: 1781771
- J Korean Med Sci.
- 2005 Oct;20(5):853-859.
- doi: 10.3346/jkms.2005.20.5.853
To examine the immunohistochemical alterations associated with the histological dedifferentiation of thyroid carcinomas, we performed staining for HBME-1, high molecular weight cytokeratin (HCK), CK 19, thyroid transcription factor-1 (TTF-1) and... -
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- Prognostic Value of Sex-Hormone Receptor Expression in Non-Muscle-Invasive Bladder Cancer
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Nam JK, Park SW, Lee SD, Chung MK
- KMID: 1799483
- Yonsei Med J.
- 2014 Sep;55(5):1214-1221.
- doi: 10.3349/ymj.2014.55.5.1214
PURPOSE: We investigated sex-hormone receptor expression as predicting factor of recurrence and progression in patients with non-muscle invasive bladder cancer. MATERIALS AND METHODS: We retrospectively evaluated tumor specimens from patients treated... -
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- High Expression of Aldo-Keto Reductase 1B10 Is an Independent Predictor of Favorable Prognosis in Patients with Hepatocellular Carcinoma
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Ha SY, Song DH, Lee JJ, Lee HW, Cho SY, Park CK
- KMID: 2070083
- Gut Liver.
- 2014 Nov;8(6):648-654.
- doi: 10.5009/gnl13406
BACKGROUND/AIMS: Upregulation of aldo-keto reductase 1B10 (AKR1B10) through the mitogenic activator protein-1 signaling pathway might promote hepatocarcinogenesis and tumor progression. The goal of this study was to evaluate the prognostic... -
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- Dipeptidyl Peptidase 10, a Novel Prognostic Marker in Colorectal Cancer
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Park HS, Yeo HY, Chang HJ, Kim KH, Park JW, Kim BC, Baek JY, Kim SY, Kim DY
- KMID: 1798131
- Yonsei Med J.
- 2013 Nov;54(6):1362-1369.
- doi: 10.3349/ymj.2013.54.6.1362
PURPOSE: The dipeptidyl peptidase IV (DPPIV) gene family exhibits multiple functions and is involved in the pathogenesis of various diseases. It has attracted pharmaceutical interest in the areas of metabolic... -
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- Expressions of HSP70 and HSP27 in Hepatocellular Carcinoma
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Joo M, Chi JG, Lee H
- KMID: 1781767
- J Korean Med Sci.
- 2005 Oct;20(5):829-834.
- doi: 10.3346/jkms.2005.20.5.829
The heat shock proteins (HSPs) are ubiquitous molecules induced in cells exposed to various stress conditions, including carcinogenesis. The HSP70 and HSP27 among HSPs are of special relevance in human... -
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- 15-Hydroxyprostaglandin Dehydrogenase in Colorectal Mucosa as a Potential Biomarker for Predicting Colorectal Neoplasms
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Lee HJ, Yang DH, Ryu YM, Song M, Song HJ, Jung KW, Kim KJ, Ye BD, Byeon JS, Choi EK, Yang SK, Kim JH, Myung SJ
- KMID: 1793019
- J Korean Med Sci.
- 2013 Aug;28(8):1154-1160.
- doi: 10.3346/jkms.2013.28.8.1154
15-Hydroxyprostaglandin dehydrogenase (15-PGDH) is downregulated during the early stages of colorectal carcinogenesis. The aim of the present study was to investigate the potential role of 15-PGDH in normal-appearing colorectal mucosa... -
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- Differential Expression of E-Cadherin, beta-Catenin, and S100A4 in Intestinal Type and Nonintestinal Type Ampulla of Vater Cancers
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Sung R, Kang L, Han JH, Choi JW, Lee SH, Lee TH, Park SH, Kim HJ, Lee ES, Kim YS, Choi YW, Park SM
- KMID: 1774534
- Gut Liver.
- 2014 Jan;8(1):94-101.
BACKGROUND/AIMS: Epithelial-mesenchymal transition (EMT)-related proteins may exhibit differential expression in intestinal type or pancreatobiliary type ampulla of Vater carcinomas (AVCs). We evaluated the expression of E-cadherin, beta-catenin, and S100A4 in... -
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- Clinicopathological Characteristics and Predictive Markers of Early Gastric Cancer with Recurrence
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Kim JW, Hwang I, Kim MJ, Jang SJ
- KMID: 1783148
- J Korean Med Sci.
- 2009 Dec;24(6):1158-1164.
- doi: 10.3346/jkms.2009.24.6.1158
Early gastric cancer (EGC) is a "curable" disease with a high cure rate made possible through proper surgical treatment; nonetheless, some patients sustain a disease recurrence after curative resection. The... -
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- Cyclooxygenase-2 and p53 Expression as Prognostic Indicators in Conventional Renal Cell Carcinoma
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Cho DS, Joo HJ, Oh DK, Kang JH, Kim YS, Lee KB, Kim SJ
- KMID: 2158123
- Yonsei Med J.
- 2005 Feb;46(1):133-140.
- doi: 10.3349/ymj.2005.46.1.133
The aim of this study was to investigate the relationship of cyclooxygenase (COX) -2 and p53 expression with prognosis in patients with conventional renal cell carcinoma (RCC). Formalin-fixed, paraffin-embedded tissue... -
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- Pax5 expression in Non-Hodgkin's Lymphomas and Acute Leukemias
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Zhang X, Lin Z, Kim I
- KMID: 1086735
- J Korean Med Sci.
- 2003 Dec;18(6):804-808.
- doi: 10.3346/jkms.2003.18.6.804
The Pax5 gene encodes the B-cell-specific activator protein which is a key regulator in development and differentiation of B-cell. We studied the expression of Pax5 in hematologic malignancies to evaluate... -
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- Tissue Microarray Analysis of Fas and FasL Expressions in Human Non-small Cell Lung Carcinomas; with Reference to the p53 and bcl-2 Overexpressions
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Myong NH
- KMID: 1781759
- J Korean Med Sci.
- 2005 Oct;20(5):770-776.
- doi: 10.3346/jkms.2005.20.5.770
Lack of surface Fas expression is a main route for apoptotic resistance which is considered an important mechanism of tumorigenesis and tumor progression. Fas and FasL expressions in 110 non-small... -
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- Expression of NDRG2 is related to tumor progression and survival of gastric cancer patients through Fas-mediated cell death
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Choi SC, Yoon SR, Park YP, Song EY, Kim JW, Kim WH, Yang Y, Lim JS, Lee HG
- KMID: 1091065
- Exp Mol Med.
- 2007 Dec;39(6):705-714.
Although N-myc downstream regulated gene 2 (NDRG2) has been known to be a tumor suppressor gene, the function of this gene has not been elucidated. In the present study, we... -
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- Identification of potential lung cancer biomarkers using an in vitro carcinogenesis model
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Kim JE, Koo KH, Kim YH, Sohn J, Park YG
- KMID: 1072951
- Exp Mol Med.
- 2008 Dec;40(6):709-720.
- doi: 10.3858/emm.2008.40.6.709
Lung cancer is one of the deadliest and commonly diagnosed neoplasms. Early diagnosis of this disease is critical for improving clinical outcome and prognosis. Because the early stages of lung... -
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