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Systemic White Blood Cell Count as a Biomarker for Chronic Obstructive Pulmonary Disease: Utility and Limitations

Kim TH

  • Tuberc Respir Dis.
  • 2017 Jul;80(3):313-315.
  • doi: 10.4046/trd.2017.80.3.313
No abstract available.
Pharmacotherapy for Acute Respiratory Distress Syndrome: Limited Success to Date

Jeon K

  • Tuberc Respir Dis.
  • 2017 Jul;80(3):311-312.
  • doi: 10.4046/trd.2017.80.3.311
No abstract available.
Systemic White Blood Cell Count as a Biomarker Associated with Severity of Chronic Obstructive Lung Disease

Koo HK, Kang HK, Song P, Park HK, Lee SS, Jung H

  • Tuberc Respir Dis.
  • 2017 Jul;80(3):304-310.
  • doi: 10.4046/trd.2017.80.3.304
BACKGROUND: Chronic obstructive pulmonary disease (COPD), is a chronic inflammatory disorder. We evaluated whether white blood cell (WBC) count, is associated with the severity of COPD, independent of other inflammatory...
Effect of Preadmission Metformin Use on Clinical Outcome of Acute Respiratory Distress Syndrome among Critically Ill Patients with Diabetes

Jo YS, Choi SM, Lee J, Park YS, Lee CH, Yim JJ, Yoo CG, Kim YW, Han SK, Lee SM

  • Tuberc Respir Dis.
  • 2017 Jul;80(3):296-303.
  • doi: 10.4046/trd.2017.80.3.296
BACKGROUND: Acute respiratory distress syndrome (ARDS) is related to high mortality and morbidity. There are no proven therapeutic measures however, to improve the clinical course of ARDS, except using low...
Review of Sarcoidosis in a Province of South Korea from 1996 to 2014

Kim MS, Park CK, Shin HJ, Seo HW, Chang J, Ahn S, Kim TO, Lim JH, Oh IJ, Kwon YS, Kim YI, Lim SC, Kim YC

  • Tuberc Respir Dis.
  • 2017 Jul;80(3):291-295.
  • doi: 10.4046/trd.2017.80.3.291
BACKGROUND: Since the introduction of endobronchial ultrasound (EBUS)–guided transbronchial needle aspiration (TBNA) of mediastinal lymph nodes, the incidence of histopathologically-confirmed sarcoidosis has increased. METHODS: The electronic medical records of Chonnam National...
Factors Related to the Diagnostic Yield of Flexible Bronchoscopy without Guidance in Bronchoscopically Invisible Peripheral Lung Lesions

Kang HS, Ha JH, Kang HH, Yeo CD, Rhee CK, Kim SK, Moon HS, Lee SH

  • Tuberc Respir Dis.
  • 2017 Jul;80(3):284-290.
  • doi: 10.4046/trd.2017.80.3.284
BACKGROUND: We aimed to analyze the factors predicting the diagnostic performance of flexible bronchoscopy without guidance in peripheral lung lesions that are endoscopically invisible. METHODS: This was a retrospective study conducted...
Determinants of Nicotine Dependence in Chronic Obstructive Pulmonary Disease

Sim YS, Lee JH, Kim KU, Ra SW, Park HY, Lee CH, Kim DK, Shin KC, Lee SH, Hwang HG, Ahn JH, Park YB, Kim YI, Yoo KH, Jeong I, Oh YM, Lee SD, KOLD Investigators

  • Tuberc Respir Dis.
  • 2017 Jul;80(3):277-283.
  • doi: 10.4046/trd.2017.80.3.277
BACKGROUND: Smoking cessation is the most powerful intervention to modify progress of chronic obstructive pulmonary disease (COPD), and nicotine dependence is one of the most important determinants of success or...
Frequency and Type of Disputed rpoB Mutations in Mycobacterium tuberculosis Isolates from South Korea

Jo KW, Lee S, Kang MR, Sung H, Kim MN, Shim TS

  • Tuberc Respir Dis.
  • 2017 Jul;80(3):270-276.
  • doi: 10.4046/trd.2017.80.3.270
BACKGROUND: A disputed rpoB mutation is a specific type of rpoB mutation that can cause low-level resistances to rifampin (RIF). Here, we aimed to assess the frequency and types of...
Effect of Prophylactic Use of Silymarin on Anti-tuberculosis Drugs Induced Hepatotoxicity

Heo E, Kim DK, Oh SH, Lee JK, Park JH, Chung HS

  • Tuberc Respir Dis.
  • 2017 Jul;80(3):265-269.
  • doi: 10.4046/trd.2017.80.3.265
BACKGROUND: The first line of anti-tuberculosis (TB) drugs are the most effective standard of drugs for TB. However, the use of these drugs is associated with hepatotoxicity. Silymarin has protective...
The Role of N-Acetyl Transferases on Isoniazid Resistance from Mycobacterium tuberculosis and Human: An In Silico Approach

Unissa AN, Sukumar S, Hanna LE

  • Tuberc Respir Dis.
  • 2017 Jul;80(3):255-264.
  • doi: 10.4046/trd.2017.80.3.255
BACKGROUND: N-acetyl transferase (NAT) inactivates the pro-drug isoniazid (INH) to N-acetyl INH through a process of acetylation, and confers low-level resistance to INH in Mycobacterium tuberculosis (MTB). Similar to NAT...
ACN9 Regulates the Inflammatory Responses in Human Bronchial Epithelial Cells

Jeong JH, Kim J, Kim J, Heo HR, Jeong JS, Ryu YJ, Hong Y, Han SS, Hong SH, Lee SJ, Kim WJ

  • Tuberc Respir Dis.
  • 2017 Jul;80(3):247-254.
  • doi: 10.4046/trd.2017.80.3.247
BACKGROUND: Airway epithelial cells are the first line of defense, against pathogens and environmental pollutants, in the lungs. Cellular stress by cadmium (Cd), resulting in airway inflammation, is assumed to...
Evaluation of Appropriate Management of Chronic Obstructive Pulmonary Disease in Korea: Based on Health Insurance Review and Assessment Service (HIRA) Claims

Chung SM, Lee SY

  • Tuberc Respir Dis.
  • 2017 Jul;80(3):241-246.
  • doi: 10.4046/trd.2017.80.3.241
Chronic obstructive pulmonary disease (COPD) is an ambulatory care-sensitive condition, and effective treatment of outpatients can prevent worsening of the illness and hospitalization. Current COPD guidelines provide appropriate guidance for...
Summary of the Chronic Obstructive Pulmonary Disease Clinical Practice Guideline Revised in 2014 by the Korean Academy of Tuberculosis and Respiratory Disease

Yoon HK, Park YB, Rhee CK, Lee JH, Oh YM, Committee of the Korean COPD Guideline 2014

  • Tuberc Respir Dis.
  • 2017 Jul;80(3):230-240.
  • doi: 10.4046/trd.2017.80.3.230
Chronic obstructive pulmonary disease (COPD) results in high morbidity and mortality among patients both domestically and globally. The Korean clinical practice guideline for COPD was revised in 2014. It was...
Recent Trends in the Prevalence of Chronic Obstructive Pulmonary Disease in Korea

Hwang YI, Park YB, Yoo KH

  • Tuberc Respir Dis.
  • 2017 Jul;80(3):226-229.
  • doi: 10.4046/trd.2017.80.3.226
Chronic obstructive pulmonary disease (COPD) had been considered the only major disease that is continuing to increase in prevalence. There were a few studies about the change of the prevalence...
Current Epidemiological Data on Asthma Management in South Korea from Qualitative Assessment of Asthma Management by Health Insurance Review and Assessment Service (HIRA)

Kim SR, Lee YC, Sung MJ, Bae HW

  • Tuberc Respir Dis.
  • 2017 Jul;80(3):221-225.
  • doi: 10.4046/trd.2017.80.3.221
Since 2015, the Health Insurance Review and Assessment Service (HIRA) has performed annual qualitative assessments of asthma management provided by all medical institutions that care for asthma patients in Korea....

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