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10 results

A Case Report of Three Patients with Nontuberculous Mycobacterial Pulmonary Disease Caused by Mycobacterium kansasii

Koh WJ, Kwon OJ, Suh GY, Chung MP, Kim H, Lee NY, Kim TS, Lee KS, Park EM, Park YK, Bai GH

  • Tuberc Respir Dis.
  • 2003 Apr;54(4):459-466.
Mycobacterium kansasii is the second most common cause of nontuberculous mycobacterial pulmonary disease in Western countries and Japan. The clinical and radiological features of pulmonary disease caused by M. kansasii...
Effect of FK506 and Cyclosporin A on I(kappa)B(alpha) Degradation and IKK Pathway in Bronchial Epithelial Cells, Monocytes, Lymphocytes and Alveolar Macrophages

Yoon HI, Lee CH, Lee HS, Lee CT, Kim YW, Han SK, Shim YS, Yoo CG

  • Tuberc Respir Dis.
  • 2003 Apr;54(4):449-458.
BACKGROUND: Cyclosporin A(CsA) and tacrolimus(FK506) have been widely used as immunosuppressants. The effects of CsA, or FK506, on the IkappaB/NF-kappaB pathway have been shown to vary according to the cell...
Effect of Dexamethasone on Gene Expression of Surfactant Protein B and Surfactant Protein C

Park IS, Sohn JW, Yoon HJ, Shin DH, Park SS

  • Tuberc Respir Dis.
  • 2003 Apr;54(4):439-448.
BACKGROUND: Surfactant protein B(SP-B) and surfactant protein C(SP-C) are important in accelerating surface spreading of surfactant phospholipid. The glucocorticoids accelerate the morphologic differentiation of epithelial cells into type II cells...
The Changes of Physiologic Parameters with Time in Steroid treated-Late Acute Respiratory Distress Syndrome Patients

Jeon IS, Suh GY, Koh WJ, Pyun YJ, Kang EH, Ham HS, Oui M, Chung MP, Kim H, Kwon OJ

  • Tuberc Respir Dis.
  • 2003 Apr;54(4):429-438.
BACKGROUND: The mortality from acute respiratory distress syndrome(ARDS) is > 40-50%. Although some prospective trials have failed to demonstrate a survival benefit of steroids in the early stages of ARDS,...
Clinical Response to Etoposide Plus Carboplatin and Topotecan Chemotherapy in Small Cell Lung Cancer

Park KH, Cho GJ, Ju JY, Son CY, Wi JO, Kim KS, Kim YI, Lim SC, Kim YC, Park KO

  • Tuberc Respir Dis.
  • 2003 Apr;54(4):415-428.
BACKGROUND: This study assessed the efficacy and toxicity of etoposide and carboplatin(EC) combination regimen as a first line therapy for small cell lung cancer(SCLC), and determined the efficacy and toxicity...
The Mechanism of Proteasome Inhibitor-Induced Apoptosis in Lung Cancer Cells

Kim CH, Lee KH, Lee CT, Kim YW, Han SK, Shim YS, Yoo CG

  • Tuberc Respir Dis.
  • 2003 Apr;54(4):403-414.
BACKGROUND: Proteasome inhibitors can promote either cell survival or programmed cell death, depending on both the specific type and proliferative status of the cell. However, it is not well known...
A Pilot Study of Bone Mineral Density in Men with Chronic Obstructive Pulmonary Disease

Bae YO, Han MS, Lee SK, Kim JN, Kim JS, Kim J, Cho Y, Lee YD

  • Tuberc Respir Dis.
  • 2003 Apr;54(4):395-402.
BACKGROUND: Patients with chronic obstructive pulmonary disease (COPD) are at increased risk for osteoporosis, which has implications for mobility and even mortality. The goal of this pilot study was to...
Prevalence of Combined Bronchial Asthma with COPD in Patients with Moderate to Severe Air flow Limitation

Rhee YK, In BH, Lee YD, Lee YC, Lee HB

  • Tuberc Respir Dis.
  • 2003 Apr;54(4):386-394.
BACKGROUND: ATS(American Thoracic Society) defined new guidelines for COPD(chronic obstructive lung disease) in April 2001, following the results of the global initiative for chronic obstructive lung disease. The most important...
Does the Layman Understand "the Whistling Sounds when Breathing out" as Real Wheezing?

Jang SH, Jung SH, Eom KS, Shin T, Kim CH, Bahn JW, Kim DG, Park MJ, Hyun IG, Jung KS

  • Tuberc Respir Dis.
  • 2003 Apr;54(4):378-385.
BACKGROUND: Wheezing is an important clue in the diagnosis of asthma. Previously, a Korean National asthma survey used a written questionnaire, containing the question, "Have you ever experienced a breathing...
Polymorphisms of HLA-DRB1 and -DQB1 Genes in Korean Patients with Pulmonary Tuberculosis

Park MH, Song EY, Kwon SY, Park H, Han SK, Shim YS

  • Tuberc Respir Dis.
  • 2003 Apr;54(4):367-377.
BACKGROUND: It is well known that only 10% of those infected with Mycobacterium tuberculosis actually develop clinical disease, indicating the existence of host genetic factors regulating disease expression. In this...

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