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Occurrence of vertebral fracture more closely associated with decreased anteroposterior than lateral lumbar bone mineral density

Tsuchie H, Miyakoshi , Kasukawa Y, Nishi T, Abe H, Segawa T, Shimada Y

  • KMID: 2309514
  • Osteoporos Sarcopenia.
  • 2016 Mar;2(1):38-40.
OBJECTIVES: While it has been pointed out that an anteroposterior (AP) view of the lumbar spine may lead to overestimation of the bone mineral density (BMD), a lateral view is...
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Analysis of bone in adenine-induced chronic kidney disease model rats

Saito H, Miyakoshi N, Kasukawa Y, Nozaka K, Tsuchie H, Sato C, Abe K, Shoji R, Shimada Y

Objectives The purpose of this study is to investigate the stage of chronic kidney disease (CKD) in adenine-induced CKD model rats by serum analyses, and to examine bone mineral density (BMD),...
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Combined treatment with minodronate and vitamin C increases bone mineral density and strength in vitamin C-deficient rats

Segawa T, Miyakoshi , Kasukawa Y, Aonuma H, Tsuchie H, Shimada Y

  • KMID: 2309513
  • Osteoporos Sarcopenia.
  • 2016 Mar;2(1):30-37.
OBJECTIVES: Reduced bone quality caused by vitamin C deficiency in older persons may lead to incidental fragility fractures during bisphosphonate treatment, although bisphosphonate increases bone mineral density (BMD). This study...
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Effects of eldecalcitol and ibandronate on secondary osteoporosis and muscle wasting in rats with adjuvant-induced arthritis

Ono Y, Miyakoshi , Kasukawa Y, Nagasawa H, Tsuchie H, Akagawa M, Nagahata I, Yuasa Y, Sato C, Shimada Y

OBJECTIVES: Rheumatoid arthritis (RA) is characterized by chronic inflammation of the synovium, progressive erosion of the articular cartilage, and joint destruction. RA also causes secondary osteoporosis and muscle wasting. We...
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Effects of combined therapy of alendronate and low-intensity pulsed ultrasound on metaphyseal bone repair after osteotomy in the proximal tibia of glucocorticoid-induced osteopenia rats

Kawano T, Miyakoshi , Kasukawa Y, Hongo M, Tsuchie H, Sato C, Fujii M, Suzuki M, Akagawa M, Ono Y, Yuasa Y, Nagahata I, Shimada Y

OBJECTIVES: Glucocorticoid (GC) treatment inhibits activation of runt-related transcription factor 2 (Runx2), which is essential for osteoblast differentiation from stem cells. As a result, GC treatment results in bone loss,...
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