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Environmental-Genetic Interactions in the Pathogenesis of Parkinson's Disease

Tsuboi Y

To date, numerous case-control studies have shown the complexity of the pathogenesis of Parkinson's disease (PD). In terms of genetic factors, several susceptibility genes are known to contribute to the...
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Perry Disease: Concept of a New Disease and Clinical Diagnostic Criteria

Tsuboi Y, Mishima T, Fujioka S

Perry disease is a hereditary neurodegenerative disease with autosomal dominant inheritance. It is characterized by parkinsonism, psychiatric symptoms, unexpected weight loss, central hypoventilation, and transactive-response DNA-binding protein of 43kD (TDP-43)...
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