- The Effect of Metformin on Male Reproductive Function and Prostate: An Updated Review
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Tseng CH
- KMID: 2523633
- World J Mens Health.
- 2022 Jan;40(1):11-29.
- doi: 10.5534/wjmh.210001
Metformin is the first-line oral antidiabetic drug that shows multiple pleiotropic effects of anti-inflamation, anti-cancer, antiaging, anti-microbia, anti-atherosclerosis, and immune modulation. Metformin’s effects on men’s related health are reviewed here,... -
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- Safety considerations for withdrawal of nucleos(t)ide analogues in patients with chronic hepatitis B: First, do no harm
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Hsu YC, Tseng CH, Kao JH
- KMID: 2546375
- Clin Mol Hepatol.
- 2023 Oct;29(4):869-890.
- doi: 10.3350/cmh.2022.0420
Nucleos(t)ide analogues (NA) are widely used to treat hepatitis B virus (HBV) infection, but they cannot eradicate the virus and treatment duration can be lifelong if the endpoint is set... -
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- Pioglitazone and Prostate Cancer Risk in Taiwanese Male Patients with Type 2 Diabetes: A Retrospective Cohort Study
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Tseng CH
- KMID: 2537124
- World J Mens Health.
- 2023 Jan;41(1):119-128.
- doi: 10.5534/wjmh.210157
Purpose: This study investigated prostate cancer risk associated with pioglitazone use. Materials and Methods: The Taiwan’s National Health Insurance database was used to create a propensity score-matched cohort of male patients... -
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- Effect of Metformin on Lower Urinary Tract Symptoms in Male Patients with Type 2 Diabetes Mellitus: A Retrospective Cohort Study in Taiwan
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Tseng CH
- KMID: 2543323
- World J Mens Health.
- 2023 Jul;41(3):680-691.
- doi: 10.5534/wjmh.220133
Purpose This study investigated the risk of lower urinary tract symptoms (LUTS)/benign prostatic hyperplasia (BPH) associated with metformin use. Materials and Methods We used the database of Taiwan’s National Health Insurance to create... -
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- Hepatitis B core-related antigen dynamics and risk of subsequent clinical relapses after nucleos(t)ide analog cessation
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Tsai YN, Wu JL, Tseng CH, Chen TH, Wu YL, Chen CC, Fang YJ, Yang TH, Nguyen MH, Lin JT, Hsu YC
- KMID: 2549386
- Clin Mol Hepatol.
- 2024 Jan;30(1):98-108.
- doi: 10.3350/cmh.2023.0194
Background/Aims: Finite nucleos(t)ide analog (NA) therapy has been proposed as an alternative treatment strategy for chronic hepatitis B (CHB), but biomarkers for post-treatment monitoring are limited. We investigated whether measuring... -
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- Antiviral therapy for chronic hepatitis B with mildly elevated aminotransferase: A rollover study from the TORCH-B trial
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Hsu YC, Chen CY, Tseng CH, Chen CC, Lee TY, Bair MJ, Chen JJ, Huang YT, Chang IW, Chang CY, Wu CY, Wu MS, Mo LR, Lin JT
- KMID: 2563421
- Clin Mol Hepatol.
- 2025 Jan;31(1):213-226.
- doi: 10.3350/cmh.2024.0640
Background/Aims: Treatment indications for patients with chronic hepatitis B (CHB) remain contentious, particularly for patients with mild alanine aminotransferase (ALT) elevation. We aimed to evaluate treatment effects in this patient... -
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