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Immune Response of BALB/c Mice toward Putative Calcium Transporter Recombinant Protein of Trichomonas vaginalis

Mendoza-Oliveros T, Arana-Argáez V, Alvaréz-Sánchez LC, Lara-Riegos J, Alvaréz-Sánchez ME, Torres-Romero JC

Trichomoniasis is a common sexually transmitted infection caused by Trichomonas vaginalis, which actually does not exist a vaccine for control or prevention. Thus, the identification of new and potent immunogens...
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Comparison of Two PCR Assays for Trichomonas vaginalis

Noh CS, Kim SS, Park SY, Moon HS, Hong Y, Ryu JS

PCR is known to be the most sensitive method for diagnosing Trichomonas vaginalis infections. This study aimed to compare the sensitivity of a PCR assay for trichomoniasis (HY-PCR) developed in...
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Comparison of Seropositivity to Trichomonas vaginalis between Men with Prostatic Tumor and Normal Men

Kim JH, Moon HS, Kim KS, Hwang HS, Ryu JS, Park SY

Trichomoniasis is the most common curable sexually-transmitted infection. Most Trichomonas vaginalis-infected men are asymptomatic and can remain undiagnosed and untreated, and this has been thought to result in chronic persistent...
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Are vaginal swabs comparable to cervical smears for human papillomavirus DNA testing?

Coorevits , Traen A, Bingé L, Van Dorpe , Praet M, Boelens J, Padalko E

OBJECTIVE: Human papillomavirus (HPV) testing is widely incorporated into cervical cancer screening strategies. Current screening requires pelvic examination for cervical sampling, which may compromise participation. The acceptance could be raised...
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Trichomonas vaginalis α-Actinin 2 Modulates Host Immune Responses by Inducing Tolerogenic Dendritic Cells via IL-10 Production from Regulatory T Cells

Lee HY, Kim J, Ryu JS, Park SJ

Trichomonas vaginalis is a pathogen that triggers severe immune responses in hosts. T. vaginalis α-actinin 2, Tvα-actinin 2, has been used to diagnose trichomoniasis. This study was undertaken to examine...
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Interaction between Trichomonas vaginalis and the Prostate Epithelium

Kim JH, Han IH, Kim SS, Park SJ, Min DY, Ahn MH, Ryu JS

Most men infected with Trichomonas vaginalis are asymptomatic and can remain undiagnosed and untreated. This has been hypothesized to result in chronic persistent prostatic infection. Adhesion of the protozoan organisms...
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Differential Protein Expressions in Virus-Infected and Uninfected Trichomonas vaginalis

He D, Pengtao G, Ju Y, Jianhua L, He L, Guocai Z, Xichen Z

Protozoan viruses may influence the function and pathogenicity of the protozoa. Trichomonas vaginalis is a parasitic protozoan that could contain a double stranded RNA (dsRNA) virus, T. vaginalis virus (TVV)....
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Optimization of Trichomonas vaginalis Diagnosis during Pregnancy at a University Hospital, Argentina

Testardini P, Vaulet ML, Entrocassi AC, Menghi C, Eliseht MC, Gatta C, Losada M, Touzón MS, Corominas , Vay C, Tatti S, Famiglietti A, Fermepin M, Perazzi B

The aim of this study was to evaluate different methods for Trichomonas vaginalis diagnosis during pregnancy in order to prevent maternal and perinatal complications. A total of 386 vaginal exudates...
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Prevalence of Trichomoniasis by PCR in Women Attending Health Screening in Korea

Kim SR, Kim JH, Gu NY, Kim YS, Hong YC, Ryu JS

Trichomoniasis is the most common curable sexually-transmitted infection (STI) worldwide. There are few reports on the prevalence of Trichomonas vaginalis in Korea. The purpose of this study was to examine...
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Inflammatory Responses in a Benign Prostatic Hyperplasia Epithelial Cell Line (BPH-1) Infected with Trichomonas vaginalis

Kim SS, Kim JH, Han IH, Ahn MH, Ryu JS

Trichomonas vaginalis causes the most prevalent sexually transmitted infection worldwide. Trichomonads have been detected in prostatic tissues from prostatitis, benign prostatic hyperplasia (BPH), and prostate cancer. Chronic prostatic inflammation is...
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Prevalence of Trichomonas vaginalis in Women Visiting 2 Obstetrics and Gynecology Clinics in Daegu, South Korea

Goo YK, Shin WS, Yang HW, Joo SY, Song SM, Ryu JS, Lee WM, Kong HH, Lee WK, Lee SE, Lee WJ, Chung DI, Hong Y

This study explored epidemiological trends in trichomoniasis in Daegu, South Korea. Wet mount microscopy, PCR, and multiplex PCR were used to test for Trichomonas vaginalis in vaginal swab samples obtained...
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Influence of 120 kDa Pyruvate:Ferredoxin Oxidoreductase on Pathogenicity of Trichomonas vaginalis

Song HO

Trichomonas vaginalis is a flagellate protozoan parasite and commonly infected the lower genital tract in women and men. Iron is a known nutrient for growth of various pathogens, and also...
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Involvement of PI3K/AKT and MAPK Pathways for TNF-alpha Production in SiHa Cervical Mucosal Epithelial Cells Infected with Trichomonas vaginalis

Yang JB, Quan JH, Kim YE, Rhee YE, Kang BH, Choi IW, Cha GH, Yuk JM, Lee YH

Trichomonas vaginalis induces proinflammation in cervicovaginal mucosal epithelium. To investigate the signaling pathways in TNF-alpha production in cervical mucosal epithelium after T. vaginalis infection, the phosphorylation of PI3K/AKT and MAPK...
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Activation of MAPK Is Required for ROS Generation and Exocytosis in HMC-1 Cells Induced by Trichomonas vaginalis-Derived Secretory Products

Narantsogt G, Min A, Nam YH, Lee YA, Kim KA, Agvaandaram G, Dorjsuren , El-Benna J, Shin MH

Trichomonas vaginalis is a flagellated protozoan parasite that causes vaginitis and cervicitis in women and asymptomatic urethritis and prostatitis in men. Mast cells have been reported to be predominant in...
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Trichomonas vaginalis Metalloproteinase Induces mTOR Cleavage of SiHa Cells

Quan JH, Choi IW, Yang JB, Zhou W, Cha GH, Zhou Y, Ryu JS, Lee YH

Trichomonas vaginalis secretes a number of proteases which are suspected to be the cause of pathogenesis; however, little is understood how they manipulate host cells. The mammalian target of rapamycin...
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Prevalence of Trichomonas vaginalis by PCR in Men Attending a Primary Care Urology Clinic in South Korea

Seo JH, Yang HW, Joo SY, Song SM, Lee YR, Ryu JS, Yoo ES, Lee WK, Kong HH, Lee SE, Lee WJ, Goo YK, Chung DI, Hong Y

Trichomonas vaginalis, a causative agent of trichomoniasis, may trigger symptomatic or asymptomatic nongonococcal urethritis and chronic prostatitis in men. Despite the availability of highly sensitive diagnostic tests, such as nucleic...
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Prostatic Disease Associated with Trichomonas vaginalis

Ryu JS

Trichomonas vaginalis is an extracellular protozoan parasite that binds to the epithelium of the human urogenital tract during infection, and causes contact-dependent cytotoxicity. Neutrophils, macrophages and mast cells known to...
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Superoxide Anion Production by Human Neutrophils Activated by Trichomonas vaginalis

Song HO, Ryu JS

Neutrophils are the predominant inflammatory cells found in vaginal discharges of patients infected with Trichomonas vaginalis. In this study, we examined superoxide anion (O2(.-)) production by neutrophils activated by T....
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The Dimension of Trichomonas vaginalis as Measured by Scanning Electron Microscopy

Cheon SH, Kim SR, Song HO, Ahn MH, Ryu JS

It is known that physicochemical conditions (e.g., pH, temperature, and ionic strength) affect the size of trichomonads. In this study, the sizes of 4 isolates of Trichomonas vaginalis cultured for more...
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Detection of Trichomonas vaginalis, Gardnerella vaginalis, and Candida Species in Affirm VPIII, Papanicolaou Smear Test and Gram Stain

Kim KH, Kim TH, Lee JH, Lee TJ, Lee MK

BACKGROUND: Infectious vaginitis is caused primarily by three different groups of microbial pathogens (Trichomonas vaginalis, Candida spp., and Gardnerella vaginalis). The objective of this study was to compare the Affirm...
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