- FDA initiatives to support dose optimization in oncology drug development: the less may be the better
-
Moon H
- KMID: 2538867
- Transl Clin Pharmacol.
- 2022 Jun;30(2):71-74.
- doi: 10.12793/tcp.2022.30.e9
-
- CITED
-
- Close
- SHARE
-
- Close
- A simple time-to-event model with NONMEM featuring right-censoring
-
Tran QT, Chae Jw, Bae KS, Yun Hy
- KMID: 2538868
- Transl Clin Pharmacol.
- 2022 Jun;30(2):75-82.
- doi: 10.12793/tcp.2022.30.e8
In healthcare situations, time-to-event (TTE) data are common outcomes. A parametric approach is often employed to handle TTE data because it is possible to easily visualize different scenarios via simulation.... -
- CITED
-
- Close
- SHARE
-
- Close
- Lessons from a multicenter clinical trial with an approved wearable electrocardiogram: issues and practical considerations
-
Huh KY, Jeong SI, Yoo H, Piao M, Ryu H, Kim H, Yoon YR, Seong SJ, Lee S, Kim KH
- KMID: 2538870
- Transl Clin Pharmacol.
- 2022 Jun;30(2):87-98.
- doi: 10.12793/tcp.2022.30.e7
Although wearable electrocardiograms (ECGs) are being increasingly applied in clinical settings, validation methods have not been standardized. As an exploratory evaluation, we performed a multicenter clinical trial implementing an approved... -
- CITED
-
- Close
- SHARE
-
- Close
- Therapeutic drug monitoring on the use of transplacental digoxin in fetal tachyarrhythmia: a case report
-
Jeong SI, Won H, Song I, Oh J
- KMID: 2538869
- Transl Clin Pharmacol.
- 2022 Jun;30(2):83-86.
- doi: 10.12793/tcp.2022.30.e11
Fetal tachycardia (FT) is a rare disorder and is associated with significant mortality of fetus. Digoxin is one of the antiarrhythmic agents used to treat FT via transplacental therapy. In... -
- CITED
-
- Close
- SHARE
-
- Close
- Comparative pharmacokinetics between two tablets of tramadol 37.5 mg/acetaminophen 325 mg and one tablet of tramadol 75 mg/acetaminophen 650 mg for extended-release fixed-dose combination
-
Kim HC, Yoon DY, Lee S, Jang IJ, Hong JH, Kim J
- KMID: 2538872
- Transl Clin Pharmacol.
- 2022 Jun;30(2):112-119.
- doi: 10.12793/tcp.2022.30.e12
An extended-release (ER) fixed-dose combination (FDC) of tramadol 37.5 mg/acetaminophen 325 mg was developed due to the demand for varying dosages. This study aimed to evaluate the pharmacokinetics (PKs) for... -
- CITED
-
- Close
- SHARE
-
- Close
- Bioanalytical methods for the detection of duloxetine and thioctic acid in plasma using ultra performance liquid chromatography with tandem mass spectrometry (UPLC-MS/MS)
-
Wei Z, Jeong HC, Kang YJ, Jang J, Kim MH, Shin KH
- KMID: 2538871
- Transl Clin Pharmacol.
- 2022 Jun;30(2):99-111.
- doi: 10.12793/tcp.2022.30.e10
Duloxetine and thioctic acid (TA) are standard drugs for treating diabetic neuropathy, a primary complication associated with diabetes. In this study, ultra performance liquid chromatography coupled with tandem mass spectrometry... -
- CITED
-
- Close
- SHARE
-
- Close
