- The Inhibitory Effect of siRNAs on The High Glucose-Induced Overexpression of TGF-beta1 in Mesangial Cells
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Noh HJ, Kim HC, Lee SS, Kang YN, Chae YM, Park KK
- KMID: 1778423
- J Korean Med Sci.
- 2006 Jun;21(3):430-435.
- doi: 10.3346/jkms.2006.21.3.430
Diabetic nephropathy is characterized by an expansion of the glomerular mesangium, caused by mesangial cell proliferation and an excessive accumulation of extracellar matrix (ECM) proteins, which eventually leading to glomerulosclerosis.... -
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- Synovial fluid of patients with rheumatoid arthritis induces alpha-smooth muscle actin in human adipose tissue-derived mesenchymal stem cells through a TGF-beta1-dependent mechanism
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Song HY, Kim MY, Kim KH, Lee IH, Shin SH, Lee JS, Kim JH
- KMID: 1104383
- Exp Mol Med.
- 2010 Aug;42(8):565-573.
- doi: 10.3858/emm.2010.42.8.057
Rheumatoid arthritis (RA) is a chronic, inflammatory autoimmune disorder that causes the immune system to attack the joints. Transforming growth factor-beta1 (TGF-beta1) is a secreted protein that promotes differentiation of... -
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