- The loss of expression of transforming growth factor-beta receptors correlates with the histopathologic tumor grade in bladder transitional cell carcinoma patients
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Lee DH, Yang SC, Hong SJ, Chung BH, Chung HJ, Tokunaga H, Kim IY, Song YS, Lerner SP, Morton RA
- KMID: 711624
- Yonsei Med J.
- 1999 Apr;40(2):118-123.
- doi: 10.3349/ymj.1999.40.2.118
Transforming growth factor-beta (TGF-beta), a pleiotropic growth factor, is a potent inhibitor of cellular proliferation in cells of epithelial origin. Recently, it has been suggested that a loss... -
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- Relaxin Modulates the Expression of MMPs and TIMPs in Fibroblasts of Patients with Carpal Tunnel Syndrome
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Kang YM, Lee HM, Moon SH, Kang H, Choi YR
- KMID: 2427132
- Yonsei Med J.
- 2017 Mar;58(2):415-422.
- doi: 10.3349/ymj.2017.58.2.415
PURPOSE: The aim of this study was to investigate the anti-fibrotic effect of relaxin in subsynovial fibroblasts activated by transforming growth factor beta (TGF-β). MATERIALS AND METHODS: To test the anti-fibrotic... -
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- Hypoxia Induces Connective Tissue Growth Factor mRNA Expression
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Lee YK, Kim EJ, Lee JE, Noh JW, Kim YG
- KMID: 1778159
- J Korean Med Sci.
- 2009 Jan;24(Suppl 1):S176-S182.
- doi: 10.3346/jkms.2009.24.S1.S176
Connective tissue growth factor (CTGF) is known to be a profibrotic growth factor, which mediate the fibrotic effect of transforming growth factor-beta(TGF-beta) and to stimulate cell proliferation and matrix production.... -
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- Transforming growth factor-beta1 protein, proliferation and apoptosis of oval cells in acetylaminofluorene-induced rat liver regeneration
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Park DY, Suh KS
- KMID: 646021
- J Korean Med Sci.
- 1999 Oct;14(5):531-538.
- doi: 10.3346/jkms.1999.14.5.531
Administering of 2-acetylaminofluorene (2-AAF) before a two-thirds partial hepatectomy (PHx) results in suppression of hepatocyte proliferation and stimulation of oval cell proliferation. The objectives of this study was to examine... -
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- Therapeutic Effects of Topical Application of Ozone on Acute Cutaneous Wound Healing
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Kim HS, Noh SU, Han YW, Kim KM, Kang H, Kim HO, Park YM
- KMID: 1779150
- J Korean Med Sci.
- 2009 Jun;24(3):368-374.
- doi: 10.3346/jkms.2009.24.3.368
This study was undertaken to evaluate the therapeutic effects of topical ozonated olive oil on acute cutaneous wound healing in a guinea pig model and also to elucidate its therapeutic... -
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- HCV core protein promotes liver fibrogenesis via up-regulation of CTGF with TGF-beta1
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Shin JY, Hur W, Wang JS, Jang JW, Kim CW, Bae SH, Jang SK, Yang SH, Sung YC, Kwon OJ, Yoon SK
- KMID: 755753
- Exp Mol Med.
- 2005 Apr;37(2):138-145.
Liver cirrhosis is one of the major complications of hepatitis C virus (HCV) infection, but the mechanisms underlying HCV-related fibrogenesis are still not clear. Although the roles of HCV core... -
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- The Role of Hepatitis C Virus Core Protein on Liver Fibrogenesis: A Study Using an In Vitro Co-culture System
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Shin JY, Yoon SK, Wang JS, Hur W, Ryu JS, Bae SH, Choi JY, Yang JM, Yang SH, Sung YC, Chung KW, Sun HS
- KMID: 1112191
- Korean J Gastroenterol.
- 2003 Nov;42(5):400-408.
BACKGROUND/AIMS: The study of liver fibrogenesis by hepatitis C virus (HCV) has been limited due to the lack of an efficiency in vitro culture systems. In the present study,... -
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- Role of TGF-beta1 and TGF-beta Type II Receptor in Gastric Cancer
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Park DI, Son HJ, Song SY, Choe WH, Lim YJ, Park SJ, Kim JJ, Kim YH, Rhee PL, Paik SW, Rhee JC, Choi KW
- KMID: 759605
- Korean J Intern Med.
- 2002 Sep;17(3):160-166.
BACKGROUND: TGF - beta is known as a cell growth inhibitory factor to suppress almost all cells, including the epithelial cell. Unlike normal cells, cancer cells are not affected... -
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- Individual or combined effects of enalapril and verapamil on chronic cyclosporine nephrotoxicity in rats
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Lee SK, Park JY, Yu ES, Yang WS, Kim SB, Park SK, Park JS
- KMID: 646042
- J Korean Med Sci.
- 1999 Dec;14(6):653-658.
- doi: 10.3346/jkms.1999.14.6.653
Previous studies have demonstrated that enalapril and verapamil seem to attenuate the cyclosporine nephrotoxicity. However, the mechanisms have not been completely understood, especially on molecular events. The aim of this... -
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- Inhibitory Effect of Angiotensin Blockade on Hepatic Fibrosis in Common Bile Duct-ligated Rats
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Park DH, Baik SK, Choi YH, Kim MY, Rhim DW, Kim JW, Kwon SO, Cho MY, Kim CH, Ahn SC
- KMID: 760706
- Korean J Hepatol.
- 2007 Mar;13(1):61-69.
BACKGROUNDS AND AIMS: Angiotensin receptors are found on hepatic stellate cells, which participate in hepatic fibrosis. Therefore, it is presumed that angiotensin has a role in hepatic fibrosis. The... -
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