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Modifiers of TGF-beta1 effector function as novel therapeutic targets of pulmonary fibrosis

Lee CM, Park JW, Cho WK, Zhou Y, Han B, Yoon PO, Chae J, Elias JA, Lee CG

Pulmonary fibrosis is a fatal progressive disease with no effective therapy. Transforming growth factor (TGF)-beta1 has long been regarded as a central mediator of tissue fibrosis that involves multiple organs...
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Synthesized TGF-beta s in RPE regulates cellular proliferation

Lee SC, Seong GJ, Kim SH, Kwon OW

Retinal pigment epithelial (RPE) cells transdifferentiate in culture, a transition which is accompanied by a shift in biological activity. The present study investigates whether transforming growth factor (TGF)-beta has the...
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