- A Korean Patient with Lattice Corneal Dystrophy Type IV with Leu527Arg Mutation in the TGFBI Gene
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Kim J, Lee KA, Kim EK, Lee HK
- KMID: 1792097
- Korean J Ophthalmol.
- 2014 Feb;28(1):83-85.
- doi: 10.3341/kjo.2014.28.1.83
An 87-year-old woman visited our clinic for a scheduled cataract surgery. At the time of preoperative evaluation, slit lamp examination showed lattice-shaped and granular deposits with asymmetrical patterns in the... -
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- Expression patterns of beta ig-h3 in chondrocyte differentiation during endochondral ossification
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Han MS, Kim JE, Shin HI, Kim IS
- KMID: 1094125
- Exp Mol Med.
- 2008 Aug;40(4):453-460.
- doi: 10.3858/emm.2008.40.4.453
beta ig-h3 is a TGF-beta-induced extracellular matrix protein which is expressed in many tissues including bones and cartilages. In previous reports, we showed that beta ig-h3 mediates cell adhesion and... -
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- Polymorphism in Codons 10 and 25 of the Transforming Growth Factor-beta1 Gene in Korean Population and in Patients with Liver Cirrhosis and Hepatocellular Carcinoma
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Kwon OS, Song SH, Ju KT, Chung MG, Park DK, Kim SS, Kim YS, Koo YS, Kim YK, Choi DJ, Kim JH, Hwang YJ, Byun KS, Lee CH
- KMID: 881585
- Korean J Gastroenterol.
- 2003 Sep;42(3):212-219.
BACKGROUND/AIMS: The genetic polymorphism of transforming growth factor-beta1 (TGF-beta1) at codons 10 and 25 which influences the production of TGF-beta1 is related to fibrogenesis in the lung and liver. We... -
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- Association of transforming growth factor-b1 gene polymorphisms with a hepatocellular carcinoma risk in patients with chronic hepatitis B virus infection
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Kim YJ, Lee HS, Im JP, Min BH, Kim HD, Jeong JB, Yoon JH, Kim CY, Kim MS, Kim JY, Jung JH, Kim LH, Park BL, Shin HD
- KMID: 1094701
- Exp Mol Med.
- 2003 Jun;35(3):196-202.
Transforming growth factor-b1 (TGF-beta 1) can act as both a tumor suppressor and a stimulator of tumor progression. We have examined the relationship between polymorphisms of the TGF-beta 1 gene... -
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- Role of TGF-beta1 and TGF-beta Type II Receptor in Gastric Cancer
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Park DI, Son HJ, Song SY, Choe WH, Lim YJ, Park SJ, Kim JJ, Kim YH, Rhee PL, Paik SW, Rhee JC, Choi KW
- KMID: 759605
- Korean J Intern Med.
- 2002 Sep;17(3):160-166.
BACKGROUND: TGF - beta is known as a cell growth inhibitory factor to suppress almost all cells, including the epithelial cell. Unlike normal cells, cancer cells are not affected... -
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- Association between genetic variations of the transforming growth factor beta receptor type III and asthma in a Korean population
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Kim HK, Jang TW, Jung MH, Park HW, Lee JE, Shin ES, Cho SH, Min KU, Kim YY
- KMID: 1078357
- Exp Mol Med.
- 2010 Jun;42(6):420-427.
- doi: 10.3858/emm.2010.42.6.043
Transforming growth factor-beta (TGF-beta) and its receptors have been suggested to play key roles in the pathogenesis of asthma. The aim of this study was to evaluate the effects of... -
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- Identification of a mutation in the human raloxifene response element of the transforming growth factor-3 gene
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Han KO, Kang YS, Hwang CS, Moon IG, Yim CH, Chung HY, Jang HC, Yoon HK, Han IK, Choi YK
- KMID: 2157560
- J Korean Med Sci.
- 2001 Oct;16(5):549-552.
- doi: 10.3346/jkms.2001.16.5.549
The human transforming growth factor-3 (TGF-3) is an important cytokine to maintain bone mass by inhibiting osteoclast differentiation. Recently raloxifene response element (RRE), a new enhancer with a polypurine sequence... -
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- A high concentration of genistein down-regulates activin A, Smad3 and other TGF-beta pathway genes in human uterine leiomyoma cells
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Di X, Andrews DM, Tucker CJ, Yu L, Moore AB, Zheng X, Castro L, Hermon T, Xiao H, Dixon D
- KMID: 1365905
- Exp Mol Med.
- 2012 Apr;44(4):281-292.
- doi: 10.3858/emm.2012.44.4.024
Previously, we found that high doses of genistein show an inhibitory effect on uterine leiomyoma (UtLM) cell proliferation. In this study, using microarray analysis and Ingenuity Pathways Analysis(TM), we identified... -
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- Effect of Antisense TGF-beta1 Oligodeoxynucleotides in Streptozotocin-Induced Diabetic Rat Kidney
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Jeong HS, Park KK, Kim SP, Choi IJ, Lee IK, Kim HC
- KMID: 1786815
- J Korean Med Sci.
- 2004 Jun;19(3):374-383.
- doi: 10.3346/jkms.2004.19.3.374
Transforming growth factor (TGF)-beta1 is an important fibrogenic factor that is involved in the pathogenesis of diabetic nephropathy. We evaluated the effect of circular antisense TGF-beta1 oligodeoxynucleotides (ODNs) on the... -
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