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Circadian regulation of low density lipoprotein receptor promoter activity by CLOCK/BMAL1, Hes1 and Hes6

Lee YJ, Han DH, Pak YK, Cho S

  • KMID: 1401756
  • Exp Mol Med.
  • 2012 Nov;44(11):642-652.
Low density lipoprotein receptor (LDLR) plays an important role in the cholesterol homeostasis. We examined the possible circadian regulation of LDLR and mechanism(s) underlying it. In mice, blood glucose and...
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Aberrant Cell Cycle Regulation in Cervical Carcinoma

Kim YT, Zhao M

Carcinoma of the uterine cervix is one of the most common malignancies among women worldwide. Human papillomaviruses (HPV) have been identified as the major etiological factor in cervical carcinogenesis. However,...
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Intrinsic and Extrinsic Regulation of Innate Immune Receptors

Jeong E, Lee JY

Pattern recognition receptors (PRRs) in innate immune cells play a pivotal role in the first line of host defense system. PRRs recognize pathogen-associated molecular patterns (PAMPs) or danger-associated molecular patterns...
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