- Cobalt Chloride Attenuates Oxidative Stress and Inflammation through NF-kappaB Inhibition in Human Renal Proximal Tubular Epithelial Cells
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Oh SW, Lee YM, Kim S, Chin HJ, Chae DW, Na KY
- KMID: 2069805
- J Korean Med Sci.
- 2014 Sep;29(Suppl 2):S139-S145.
- doi: 10.3346/jkms.2014.29.S2.S139
We evaluated the effect of cobalt chloride (CoCl2) on TNF-alpha and IFN-gamma-induced-inflammation and reactive oxygen species (ROS) in renal tubular epithelial cells (HK-2 cells). We treated HK-2 cells with CoCl2... -
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- A new synthetic chalcone derivative, 2-hydroxy-3',5,5'-trimethoxychalcone (DK-139), suppresses the Toll-like receptor 4-mediated inflammatory response through inhibition of the Akt/NF-kappaB pathway in BV2 microglial cells
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Lee YH, Jeon SH, Kim SH, Kim C, Lee SJ, Koh D, Lim Y, Ha K, Shin SY
- KMID: 1383799
- Exp Mol Med.
- 2012 Jun;44(6):369-377.
Microglial cells are the resident innate immune cells that sense pathogens and tissue injury in the central nervous system (CNS). Microglial activation is critical for neuroinflammatory responses. The synthetic compound... -
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- The Effects of Family History of Colorectal Cancer on the Development of Colorectal Adenoma
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Choi MY, Kim BG, Kim JW, Lee KL, Jeong JB, Lee JK, Jung YJ, Kim W, Ahn DW, Kim YH, Joo SK, Chang MS, Kwon HJ
- KMID: 1718464
- Korean J Gastroenterol.
- 2012 Jul;60(1):36-41.
- doi: 10.4166/kjg.2012.60.1.36
BACKGROUND/AIMS: Early detection of polyp is important for the prevention of colorectal cancer (CRC). There have been few studies to investigate the relationship between colorectal adenoma and family history of... -
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- Potential role of HMG CoA reductase inhibitor on oxidative stress induced by advanced glycation endproducts in vascular smooth muscle cells of diabetic vasculopathy
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Yoon SJ, Yoon YW, Lee BK, Kwon HM, Hwang KC, Kim M, Chang W, Hong BK, Lee YH, Park SJ, Min PK, Rim SJ
- KMID: 1122281
- Exp Mol Med.
- 2009 Nov;41(11):802-811.
- doi: 10.3858/emm.2009.41.11.086
Advanced glycation endproducts (AGEs)-induced vascular smooth muscle cell (VSMCs) proliferation and formation of reactive oxygen species (ROS) are emerging as one of the important mechanisms of diabetic vasculopathy but little... -
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