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Changes in enzyme activity and expression of DHFR of Toxoplasma gondii by antifolates

Baek EJ, Nam HW

The responses to antifolates of Toxoplasma gondii were investigated by measuring the dihydrofolate reductase (DHFR) activity, quantity of DHFR mRNA, and single-strand conformational polymorphism (SSCP) pattern. Pyrimethamine (PYM) and methotrexate...
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Influence of calcium ion on host cell invasion and intracellular replication by Toxoplasma gondii

Song HO, Ahn MH, Ryu JS, Min DY, Joo KH, Lee YH

Toxoplasma gondii is an obligate intracellular protozoan parasite, which invades a wide range of hosts including humans. The exact mechanisms involved in its invasion are not fully understood. This study...
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