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Zolpidem Detection and Blood Level in Acute Poisoning-suspected Patients in Emergency Departments: Review of 229 Cases

Yu J, Chang H, Won S, Yeom J, Lee A, Park NY, Oh BJ

PURPOSE: Non-benzodiazepine hypnotic drugs (including zolpidem) are associated with an increased risk of suicide and suicidal ideation. Considering the wide usage of zolpidem, this drug should be considered a possible...
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Korean Mothersafe Center 10th Anniversary: Outcome and Future Prospects

Han JY, Ahn HK, Choi JS, Yeom GJ, Lee SY, Kim YH, Hong DS, Hong SY, Yun JS, Jung HJ, Jeon HJ, Joo SH, Choi A, Jeong ES

PURPOSE: The purpose of this report is to organize the history of Korean Mothersafe, a professional teratology information center. Throughout its domestic and international activities, Mothersafe has firm role to...
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Does Nationality Matter for the Gunshot Brain Injury? Ten-Year Retrospective Observational Cadaveric Comparative Study for Gunshot TBI between Greece and Bulgaria

Nikova AS, Karakasi M, Pavlidis P, Birbilis T, Dimitrov I

OBJECTIVE: Penetrating brain trauma (PBT) caused by gunshot is one of the most lethal traumatic brain injuries (TBIs) and its management and confrontation is of great importance. METHODS: The authors searched...
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A Complex Suicide by Ligature Strangulation and Hanging Using Two Different Ligatures

Subramaniam K, Pankajakshan CN

Hanging is the most common method of suicide in Malaysia. However, hanging in combination with suicidal ligature strangulation is uncommon. The victim is a 31-year-old man, with no previous medical...
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Metoprolol treatment of dual cocaine and bupropion cardiovascular and central nervous system toxicity

Richards J, Gould JB, Laurin EG, Albertson

Cardiovascular and central nervous system (CNS) toxicity, including tachydysrhythmia, agitation, and seizures, may arise from cocaine or bupropion use. We report acute toxicity from the concomitant use of cocaine and...
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A Case Report of Cardiac Arrest Following Intentional Ingestion of Liquid Nicotine for Electronic Cigarette

Kim JH

Acute nicotine poisoning by liquid nicotine for electronic cigarettes is becoming an increasing problem worldwide. On the other hand, there are no regulations regarding its concentration, container or labelling in...
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Evaluation of Cut-off Values in Acute Acetaminophen Intoxication Following the Revised Guideline of the United Kingdom

Park SJ, Cha K, So BH, Kim HM, Jeoung WJ

PURPOSE: In 2012, a revised guideline for acute acetaminophen overdose was proposed in the UK, recommending that the treatment threshold should be lowered to 100 mcg/ml at 4 hours after...
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Relative Risk and Clinical Severity Assessment in Patients with Non-Oral Route Organophosphate Poisoning Compared with Oral Route Poisoning

Jung WJ, Yu MH, Lee Y, Kim H, Cha YS, Park KH

PURPOSE: Organophosphates, commonly used in agricultural pesticides, pose high risks and incidences of poisoning. In the present study, we investigated the relative risk and clinical severity, including laboratory results, of...
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Epigenetic profiling to environmental stressors in model and non-model organisms: Ecotoxicology perspective

Chatterjee N, Gim J, Choi J

Epigenetics, potentially heritable changes in genome function that occur without alterations to DNA sequence, is an important but understudied component of ecotoxicology studies. A wide spectrum of environmental challenge, such...
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Reminiscing on 35 years with Environmental Toxicology in Korea

Kim YH

No abstract available.
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Clinical characteristics and mortality-predictive factors analyses of glyphosate intoxication

Son CH, Lee SH, Jang TC, Kim GM, Ko SH, Seo YW

OBJECTIVE: Glyphosate intoxicated patients are increasing as glyphosate use increases. This study was conducted to analyze clinical characteristics of glyphosate intoxication patients to provide early treatment to high risk patients. METHODS:...
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Review of carcinogenicity of hexavalent chrome and proposal of revising approval standards for an occupational cancers in Korea

Kim J, Seo S, Kim Y, Kim DH

BACKGROUND: The objective of this study is to suggest revised recognition standards for occupational disease due to chromium (VI) by reflecting recent domestic and international research works and considering domestic...
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Necessity of Research on Thirdhand Smoke for Maternal and Child Health

Choe JH, Han JY

The causal relationship between cigarette smoking during pregnancy and adverse maternal and child health outcomes, such as preterm birth, low birth weight, and sudden infant death syndrome are well known....
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Acute and 13-week subchronic toxicological evaluations of turanose in mice

Chung JY, Lee J, Lee D, Kim E, Shin JH, Seok PR, Yoo SH, Kim Y

BACKGROUND/OBJECTIVES: Turanose, α-D-glucosyl-(1→3)-α-D-fructose, is a sucrose isomer which naturally exists in honey. To evaluate toxicity of turanose, acute and subchronic oral toxicity studies were conducted with ICR mice. MATERIALS AND METHODS:...
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Evaluation of the Triage TOX Drug Screen Assay for Detection of 11 Drugs of Abuse and Therapeutic Drugs

Bang HI, Jang MA, Lee YW

The demand for rapid and broad clinical toxicology screens is on the rise. Recently, a new rapid toxicology screening test, the Triage TOX Drug Screen (Alere Inc., USA), which can...
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Death Related to Nitrous Oxide Abuse: Two Cases Report

Kim JM, Choi M, Kim HN, Kim HJ, Baek T, Choi M, Ha H

Nitrous oxide is medically used as an anesthetic gas and as an additive in whipped cream production. Few cases of death from nitrous oxide intoxication have been reported in Korea....
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Annual tendency of research papers used ICR mice as experimental animals in biomedical research fields

Kim JE, Nam JH, Cho JY, Kim KS, Hwang DY

Institute of Cancer Research (ICR) mice have been widely used in various research fields including toxicology, oncology, pharmacology, and pharmaceutical product safety testing for decades. However, annual tendency of research...
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Implementing Best Practice in Critically Ill Organophosphate Poisoned Patient Through Simulation-Based Learning Program

Lee JH, Chung SP, Chung HS

PURPOSE: Despite the clinical and socio-economic impact of acute poisoned patients, many of the treatments are not standardized in Korea. Moreover, no formal training that is specifically focused on clinical...
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The Revised Korean Practice Parameter for the Treatment of Attention-Deficit Hyperactivity Disorder (III): Pharmacological Treatment

Kim HW, Kim E, Kim JH, Park J, Bahn GH, Lee YJ, Jhung K, Shin D

The objective of this review is the revision of the Korean practice parameters for the pharmacological treatment of attention-deficit hyperactivity disorder (ADHD) based on the change in the diagnostic system...
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Comparison of commonly used ICR stocks and the characterization of Korl:ICR

Shin HJ, Cho YM, Shin HJ, Kim HD, Choi KM, Kim MG, Shin HD, Chung MW

Mouse is a commonly used animal in life science studies and is classified as outbred if genetically diverse and inbred if genetically homogeneous. Outbred mouse stocks, are used in toxicology,...
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