- Limited expression of TLR9 on T cells and its functionalconsequences in patients with nonalcoholic fatty liverdisease
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Alegre NS, Garcia CC, Billordo L, Ameigeiras B, Poncino D, Benavides , Colombato , Cherñavsky AC
- KMID: 2500386
- Clin Mol Hepatol.
- 2020 Apr;26(2):216-226.
- doi: 10.3350/cmh.2019.0074
Background/Aims: Toll-like receptors (TLRs) modulate T cell responses in diverse diseases. Co-stimulation of T cell activation via TLR9 induces production of interferon gamma (IFN-γ), priming of which is critical for... -
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- Toll-like receptor 9, a possible blocker of non-alcoholicsteatohepatitis?
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Jeong SW
- KMID: 2500382
- Clin Mol Hepatol.
- 2020 Apr;26(2):185-186.
- doi: 10.3350/cmh.2020.0046
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- Association between Toll-Like Receptor 9-1237T/C Polymorphism and the Susceptibility of Inflammatory Bowel Diseases: A Meta-Analysis
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Shang J, Wang X, Wang W, Pan H, Liu S, Li L, Chen L, Xia B
- KMID: 2466365
- Yonsei Med J.
- 2016 Jan;57(1):153-164.
- doi: 10.3349/ymj.2016.57.1.153
PURPOSE: The -1237T/C polymorphism of the Toll-like receptor 9 (TLR9) gene has been implicated in the susceptibility of inflammatory bowel diseases (IBDs), but the results remain conflicting. We further investigated... -
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- Toll-Like Receptor Gene Expression during Trichinella spiralis Infection
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Kim S, Park MK, Yu HS
- KMID: 2381760
- Korean J Parasitol.
- 2015 Aug;53(4):431-438.
- doi: 10.3347/kjp.2015.53.4.431
In Trichinella spiralis infection, type 2 helper T (Th2) cell-related and regulatory T (T(reg)) cell-related immune responses are the most important immune events. In order to clarify which Toll-like receptors... -
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- Nucleic Acid Recognition and Signaling by Toll-like Receptor 9: Compartment-dependent Regulation
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Koh YS
- KMID: 2168631
- J Bacteriol Virol.
- 2011 Jun;41(2):131-132.
- doi: 10.4167/jbv.2011.41.2.131
Toll-like receptor 9 binds to DNA from bacteria or viruses and activates a signaling pathway that leads to the induction of proinflammatory cytokines and type I interferon. Adaptor complex AP-3... -
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- Toll-like receptor 9-mediated inhibition of apoptosis occurs through suppression of FoxO3a activity and induction of FLIP expression
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Lim EJ, Park DW, Lee JG, Lee CH, Bae YS, Hwang YC, Jeong JW, Chin BR, Baek SH
- KMID: 964666
- Exp Mol Med.
- 2010 Oct;42(10):712-720.
- doi: 10.3858/emm.2010.42.10.070
Synthetic oligodeoxynucleotides (ODN) with a CpG-motif are recognized by Toll-like receptor 9 (TLR9) and pleiotropic immune responses are elicited. Stimulation of macrophages with TLR9 agonist prevented apoptosis induced by serum... -
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- Toll-like receptor 9 expression and interferon-alpha secretion upon CpG-ODN stimulation in allergic subjects
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Han MY, Jee HM, Kim HY, Lee CA, Cho HJ, Hwang SG, Kim KE
- KMID: 2281257
- Korean J Pediatr.
- 2009 Sep;52(9):1015-1020.
- doi: 10.3345/kjp.2009.52.9.1015
PURPOSE: The aim of this study is to explore the effect of the Toll-like receptor 9 (TLR9) expressed in plasmacytoid dendritic cells (pDCs) that respond to antigen to Th2 immune... -
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- Toll-like receptor 9 dependent activation of MAPK and NF-kB is required for the CpG ODN-induced matrix metalloproteinase-9 expression
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Lim EJ, Lee SH, Lee JG, Kim JR, Yun SS, Baek SH, Lee C
- KMID: 1094665
- Exp Mol Med.
- 2007 Apr;39(2):239-245.
Unmethylated CpG oligodeoxynucleotides (CpG ODNs) activate immune cells to produce immune mediators. This study demonstrates that in murine macrophage RAW 264.7 cells, CpG ODN-mediated matrix metalloproteinase-9 (MMP-9) expression is regulated... -
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