- Intrinsic Cellular Defenses against Virus Infection by Antiviral Type I Interferon
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Boo KH, Yang JS
- KMID: 1779600
- Yonsei Med J.
- 2010 Jan;51(1):9-17.
- doi: 10.3349/ymj.2010.51.1.9
Intrinsic cellular defenses are non-specific antiviral activities by recognizing pathogen-associated molecular patterns (PAMPs). Toll-like receptors (TLRs), one of the pathogen recognize receptor (PRR), sense various microbial ligands. Especially, TLR2, TLR3,... -
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- The role of gut-liver axis in the pathogenesis of liver cirrhosis and portal hypertension
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Seo YS, Shah VH
- KMID: 1410889
- Clin Mol Hepatol.
- 2012 Dec;18(4):337-346.
- doi: 10.3350/cmh.2012.18.4.337
Because of the anatomical position and its unique vascular system, the liver is susceptible to the exposure to the microbial products from the gut. Although large amount of microbes colonize... -
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- Inflammation and Hepatic Fibrosis, Then Hepatocellular Carcinoma
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Kwon OS, Choi SH, Kim JH
- KMID: 2373365
- Korean J Gastroenterol.
- 2015 Dec;66(6):320-324.
- doi: 10.4166/kjg.2015.66.6.320
Inflammation is one of the most prominent characteristic features of chronic liver disease, liver fibrosis, cirrhosis, and hepatocellular carcinoma (HCC). Most of HCC cases develop in patients with cirrhosis and... -
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- NOD-Like Receptors in Infection, Immunity, and Diseases
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Kim YK, Shin JS, Nahm MH
- KMID: 2466346
- Yonsei Med J.
- 2016 Jan;57(1):5-14.
- doi: 10.3349/ymj.2016.57.1.5
Nucleotide-binding and oligomerization domain (NOD)-like receptors (NLRs) are pattern-recognition receptors similar to toll-like receptors (TLRs). While TLRs are transmembrane receptors, NLRs are cytoplasmic receptors that play a crucial role in... -
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