- Association Between Toll-Like Receptors/CD14 Gene Polymorphisms and Inflammatory Bowel Disease in Korean Population
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Kim EJ, Chung WC, Lee KM, Paik CN, Jung SH, Lee BI, Chae HS, Choi KY
- KMID: 1792982
- J Korean Med Sci.
- 2012 Jan;27(1):72-77.
- doi: 10.3346/jkms.2012.27.1.72
The innate immune response in patients who develop inflammatory bowel disease (IBD) may be abnormal. However, the exact role of Toll-like receptors (TLRs) / CD14 gene in the pathogenesis of... -
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- Multiple Signaling Molecules are Involved in Expression of CCL2 and IL-1beta in Response to FSL-1, a Toll-Like Receptor 6 Agonist, in Macrophages
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Won K, Kim SM, Lee SA, Rhim BY, Eo SK, Kim K
- KMID: 2285454
- Korean J Physiol Pharmacol.
- 2012 Dec;16(6):447-453.
- doi: 10.4196/kjpp.2012.16.6.447
TLR6 forms a heterodimer with TLR2 and TLR4. While proinflammatory roles of TLR2 and TLR4 are well documented, the role of TLR6 in inflammation is poorly understood. In order to... -
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- 7alpha-Hydroxycholesterol Elicits TLR6-Mediated Expression of IL-23 in Monocytic Cells
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Seo HC, Kim SM, Eo SK, Rhim BY, Kim K
- KMID: 2380367
- Biomol Ther.
- 2015 Jan;23(1):84-89.
- doi: 10.4062/biomolther.2014.067
We investigated the question of whether 7-oxygenated cholesterol derivatives could affect inflammatory and/or immune responses in atherosclerosis by examining their effects on expression of IL-23 in monocytic cells. 7alpha-Hydroxycholesterol (7alphaOHChol)... -
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