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Serum amyloid A inhibits RANKL-induced osteoclast formation

Oh E, Lee HY, Kim HJ, Park YJ, Seo JK, Park JS, Bae YS

When mouse bone marrow-derived macrophages were stimulated with serum amyloid A (SAA), which is a major acute-phase protein, there was strong inhibition of osteoclast formation induced by the receptor activator...
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beta1-integrin-dependent migration of microglia in response to neuron-released alpha-synuclein

Kim C, Cho ED, Kim HK, You S, Lee HJ, Hwang D, Lee SJ

Chronic neuroinflammation is an integral pathological feature of major neurodegenerative diseases. The recruitment of microglia to affected brain regions and the activation of these cells are the major events leading...
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IL-17 induces the production of IL-16 in rheumatoid arthritis

Cho ML, Jung YO, Kim KW, Park MK, Oh HJ, Ju JH, Cho YG, Min JK, Kim SI, Park SH, Kim HY

The purpose of this study was to investigate the expression of IL-16 in the rheumatoid synovium and the role of inflammatory cytokines and Toll-like receptor (TLR) ligands in IL-16 production...
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