- The loss of expression of transforming growth factor-beta receptors correlates with the histopathologic tumor grade in bladder transitional cell carcinoma patients
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Lee DH, Yang SC, Hong SJ, Chung BH, Chung HJ, Tokunaga H, Kim IY, Song YS, Lerner SP, Morton RA
- KMID: 711624
- Yonsei Med J.
- 1999 Apr;40(2):118-123.
- doi: 10.3349/ymj.1999.40.2.118
Transforming growth factor-beta (TGF-beta), a pleiotropic growth factor, is a potent inhibitor of cellular proliferation in cells of epithelial origin. Recently, it has been suggested that a loss... -
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- The 2020 Japan Society of Gynecologic Oncology guidelines for the treatment of ovarian cancer, fallopian tube cancer, and primary peritoneal cancer
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Tokunaga H, Mikami M, Nagase S, Kobayashi Y, Tabata T, Kaneuchi M, Satoh T, Hirashima Y, Matsumura N, Yokoyama Y, Kawana K, Kyo S, Aoki D, Katabuchi H
- KMID: 2526387
- J Gynecol Oncol.
- 2021 Mar;32(2):e49.
- doi: 10.3802/jgo.2021.32.e49
The fifth edition of the Japan Society of Gynecologic Oncology guidelines for the treatment of ovarian cancer, fallopian tube cancer, and primary peritoneal cancer was published in 2020. The guidelines... -
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- Lymphadenectomy issues in endometrial cancer
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Konno Y, Asano H, Shikama A, Aoki D, Tanikawa M, Oki A, Horie K, Mitsuhashi A, Kikuchi A, Tokunaga H, Terao Y, Satoh T, Ushijima K, Ishikawa M, Yaegashi N, Watari H
- KMID: 2526370
- J Gynecol Oncol.
- 2021 Mar;32(2):e25.
- doi: 10.3802/jgo.2021.32.e25
Objectives: This review aims to introduce preoperative scoring systems to predict lymph node metastasis (LNM) and ongoing clinical trials to investigate the therapeutic role of lymphadenectomy for endometrial cancer. Methods: We... -
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- Risk stratification models for para-aortic lymph node metastasis and recurrence in stage IB–IIB cervical cancer
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Matsuo K, Shimada M, Saito T, Takehara K, Tokunaga H, Watanabe Y, Todo Y, Morishige , Mikami M, Sugiyama T
- KMID: 2395238
- J Gynecol Oncol.
- 2018 Jan;29(1):e11.
- doi: 10.3802/jgo.2018.29.e11
OBJECTIVE: To examine the surgical-pathological predictors of para-aortic lymph node (PAN) metastasis at radical hysterectomy, and for PAN recurrence among women who did not undergo PAN dissection at radical hysterectomy. METHODS:... -
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- Phase 2 single-arm study on the safety of maintenance niraparib in Japanese patients with platinum-sensitive relapsed ovarian cancer
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Takehara K, Matsumoto T, Hamanishi J, Hasegawa K, Matsuura M, Miura K, Nagao S, Nakai H, Tanaka N, Tokunaga H, Ushijima K, Watari H, Yokoyama Y, Kase Y, Sumino S, Suri A, Itamochi H, Takeshima N
- KMID: 2526362
- J Gynecol Oncol.
- 2021 Mar;32(2):e21.
- doi: 10.3802/jgo.2021.32.e21
Objective: The primary objective of this study was to evaluate the safety of niraparib 300 mg/day in Japanese patients with platinum-sensitive, relapsed ovarian cancer in a maintenance setting. Methods: Phase 2,... -
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- Clinicopathologic features, treatment, prognosis and prognostic factors of neuroendocrine carcinoma of the endometrium: a retrospective analysis of 42 cases from the Kansai Clinical Oncology Group/Intergroup study in Japan
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Matsumoto , Shimokawa , Nasu K, Shikama A, Shiozaki T, Futagami M, Kai K, Nagano H, Mori T, Yano M, Sugino N, Fujimoto E, Yoshioka N, Nakagawa S, Shimada M, Tokunaga H, Yamada Y, Tsuruta T, Tasaki K, Nishikawa , Kuji S, Motohashi , Ito K, Yamada T, Teramoto N
- KMID: 2458905
- J Gynecol Oncol.
- 2019 Nov;30(6):e103.
- doi: 10.3802/jgo.2019.30.e103
OBJECTIVE: We conducted a retrospective, multi-institutional, collaborative study to accumulate cases of neuroendocrine carcinoma of the endometrium, to clarify its clinicopathologic features, treatment, prognosis and prognostic factors to collate findings... -
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