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Vocal Fold Augmentation: Current Review

Kim CS

Glottic closure is essential for vocalization and airway protection. Several pathological conditions cause glottic insufficiency, such as vocal fold paralysis and presbylarynx, which is the age-related atrophy of laryngeal muscle....
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The in vitro analysis of migration and polarity of blastema cells in the extracellular matrix derived from bovine mesenteric in the presence of fibronectin

Kohannezhad K, Norouzi S, Tafazoli M, Soleymani S, Shahri NM, Tavassoli A

Cell migration is an essential process in embryonic development, wound healing, and pathological conditions. Our knowledge of cell migration is often based on the two dimentional evaluation of cell movement,...
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Use of Human Gingival Fibroblasts for Pre-Vascularization Strategies in Oral Tissue Engineering

Smirani R, Rémy M, Devillard R, Naveau A

BACKGROUND: Cocultures of human gingival fibrobasts (hGF) and endothelial cells could enhance regeneration and repair models as well as improve vascularization limitations in tissue engineering. The aim of this study...
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Use of stem cells in bone regeneration in cleft palate patients: review and recommendations

Amiri MA, Lavaee F, Danesteh H

This study was conducted to review the efficacy of different sources of stem cells in bone regeneration of cleft palate patients. The majority of previous studies focused on the transplantation...
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Effects of Induction Culture on Osteogenesis of Scaffold-Free Engineered Tissue for Bone Regeneration Applications

Park HM, Kim SH, Choi BH, Park SH

BACKGROUND: Restoration of the bone defects caused by infection or disease remains a challenge in orthopedic surgery. In recent studies, scaffold-free engineered tissue with a self-secreted extracellular matrix has been...
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Tissue Engineering with Compact Bone-Derived Cell Spheroids Enables Bone Formation around Transplanted Tooth

Matsumura N, Li X, Uchikawa-Kitaya E, Li N, Dong H, Chen K, Yoshizawa M, Kagami H

BACKGROUND: Although tooth transplantation is a desirable treatment option for congenital defects of permanent teeth in children, transplantation to a narrow alveolar ridge is not feasible. In this study, we...
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Sources, Characteristics, and Therapeutic Applications of Mesenchymal Cells in Tissue Engineering

Gonzalez-Vilchis RA, Piedra-Ramirez A, Patinõ-Morales CC, Sanchez-Gomez C, Beltran-Vargas NE

Tissue engineering (TE) is a therapeutic option within regenerative medicine that allows to mimic the original cell environment and functional organization of the cell types necessary for the recovery or...
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Engineering of Immune Microenvironment for Enhanced Tissue Remodeling

Ko GR, Lee JS

The capability to restore the structure and function of tissues damaged by fatal diseases and trauma is essential for living organisms. Various tissue engineering approaches have been applied in lesions...
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Fabrication Parameter-Dependent Physico-Chemical Properties of Thiolated Gelatin/PEGDA Interpenetrating Network Hydrogels

Kim S, Choi Y, Lee W, Kim K

BACKGROUND: The development of three-dimensional hydrogels using polymeric biomaterials is a key technology for tissue engineering and regenerative medicine. Successful tissue engineering requires the control and identification of the physicochemical...
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Electrospinning Fabrication Methods to Incorporate Laminin in Polycaprolactone for Kidney Tissue Engineering

Baskapan B, Callanan A

BACKGROUND: Today’s treatment options for renal diseases fall behind the need, as the number of patients has increased considerably over the last few decades. Tissue engineering (TE) is one avenue...
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Preparation and In Vitro Characterization of Gelatin Methacrylate for Corneal Tissue Engineering

Yan Y, Cao Y, Cheng R, Shen Z, Zhao Y, Zhang Y, Zhou G, Sang S

BACKGROUND: Corneal disease is second only to cataract considered as the leading cause of blindness in the world, with high morbidity. Construction of corneal substitutes In Vitro by tissue engineering...
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The Application of Cartilage Tissue Engineering with Cell-Laden Hydrogel in Plastic Surgery: A Systematic Review

Wang G, Zhang X, Bu X, An Y, Bi H, Zhao Z

BACKGROUND: As a contour-supporting material, the cartilage has a significant application value in plastic surgery.Since the development of hydrogel scaffolds with sufficient biomechanical strength and high biocompatibility, cell-laden hydrogels have...
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Vascularization of Microvascular Fragment Isolates from Visceral and Subcutaneous Adipose Tissue of Mice

Später T, Marschall JE, Brücker LK, Nickels RM, Metzger W, Menger MD, Laschke MW

BACKGROUND: Adipose tissue-derived microvascular fragments (MVF) represent effective vascularization units for tissue engineering. Most experimental studies in rodents exclusively use epididymal adipose tissue as a visceral fat source for MVF...
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Autologous blood derived cell therapy in maxillofacial bone graft surgery

Park JY

Tissue regeneration is one of the ultimate goals of maxillofacial surgery and various types of tissue engineering technologies have been utilized in clinics. Healthy resources of host cells and growth...
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Biomaterials-based Approaches for Cardiac Regeneration

Vasu S, Zhou J, Chen J, Johnston PV, Kim DH

The limited ability of cardiomyocytes to proliferate is a major cause of mortality and morbidity in cardiovascular diseases. There exist therapies for cardiac regeneration that are cell-based as well as...
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Patient-Specific Tumor Microenvironment Models

Lee JW, Kim J, Shin Y, Chi BH, Kim JH, Choi SY

The heterogeneity of cancer makes it difficult to predict the prognosis of treatment. There is still a lack of preclinical model systems that reflect the clinical characteristics of patients who...
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Comparative characteristic study from bone marrow-derived mesenchymal stem cells

Purwaningrum M, Jamilah NS, Purbantoro SD, Sawangmake C, Nantavisai S

Tissue engineering has been extensively investigated and proffered to be a potential platform for novel tissue regeneration. The utilization of mesenchymal stem cells (MSCs) from various sources has been widely...
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Biomimetic Biphasic Electrospun Scaffold for Anterior Cruciate Ligament Tissue Engineering

Tang Y, Tian J, Li L, Huang L, Shen Q, Guo S, Jiang Y

Background: Replacing damaged anterior cruciate ligaments (ACLs) with tissue-engineered artificial ligaments is challenging because ligament scaffolds must have a multiregional structure that can guide stem cell differentiation. Here, we designed a...
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Effect of Leukocyte-Platelet Rich Fibrin (L-PRF) on Tissue Regeneration and Proliferation of Human Gingival Fibroblast Cells Cultured Using a Modified Method

Mudalal M, Wang Z, Mustafa S, Liu Y, Wang Y, Yu J, Wang S, Sun X, Zhou Y

Background: An in vitro study on rapid culturing method of human gingival fibroblast cells (HGFCs) was established to investigate the potential use of the leukocyte-platelet rich fibrin (L-PRF) in tissue engineering...
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Effects of Androgen Receptor Overexpression on Chondrogenic Ability of Rabbit Articular Chondrocytes

Hui L, Shoumei X, Zhoujing Z, Kuang G, Duohong Z, Jiacai H, Yong Z

BACKGROUND: The role of sex hormones and their receptors has drawn much attention in the process of cartilage regeneration. This study aimed to investigate the effect of androgen receptor (AR)...
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