- Galectin-9 is Involved in Immunosuppression Mediated by Human Bone Marrow-derived Clonal Mesenchymal Stem Cells
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Kim SN, Lee HJ, Jeon MS, Yi T, Song SU
- KMID: 2150853
- Immune Netw.
- 2015 Oct;15(5):241-251.
- doi: 10.4110/in.2015.15.5.241
Bone marrow-derived mesenchymal stem cells (MSCs) have immunomodulatory properties and can suppress exaggerated pro-inflammatory immune responses. Although the exact mechanisms remain unclear, a variety of soluble factors are known to... -
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- Identification of CCL1 as a Gene Differentially Expressed in CD4+ T Cells Expressing TIM-3
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Jun KJ, Lee MJ, Shin DC, Woo MY, Kim K, Park S
- KMID: 1449811
- Immune Netw.
- 2011 Aug;11(4):203-209.
- doi: 10.4110/in.2011.11.4.203
BACKGROUND: T cell immunoglobulin mucin containing molecule (TIM)-3 is expressed in differentiated Th1 cells and is involved in the suppression of the cytokine production by these cells. However, the regulation... -
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- T-Cell Dysfunction and Inhibitory Receptors in Hepatitis C Virus Infection
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Lee J, Suh WI, Shin EC
- KMID: 2150670
- Immune Netw.
- 2010 Aug;10(4):120-125.
- doi: 10.4110/in.2010.10.4.120
Dysfunction of the virus-specific T cells is a cardinal feature in chronic persistent viral infections such as one caused by hepatitis C virus (HCV). In chronic HCV infection, virus-specific dysfunctional... -
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- The Binding Properties of Glycosylated and Non-Glycosylated Tim-3 Molecules on CD4+CD25+ T Cells
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Lee MJ, Heo YM, Hong SH, Kim K, Park S
- KMID: 1474596
- Immune Netw.
- 2009 Apr;9(2):58-63.
- doi: 10.4110/in.2009.9.2.58
BACKGROUND: T cell immunoglobulin and mucin domain containing 3 protein (Tim-3) expressed on terminally differentiated Th1 cells plays a suppressive role in Th1-mediated immune responses. Recently, it has been shown... -
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- Molecular variations in Th1-specific cell surface gene Tim-3
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Chae SC, Song JH, Pounsambath P, Yuan HY, Lee JH, Kim JJ, Lee YC, Chung HT
- KMID: 1097110
- Exp Mol Med.
- 2004 Jun;36(3):274-278.
The family of T-cell immunoglobulin domain and mucin domain (TIM) proteins is identified to be expressed on T cells. A member of Tim family, Tim-3 (T cell immunoglobulin mucin 3)... -
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