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Development of thymic lymphomas in mice disrupted of Brca2 allele in the thymus

Park PG, Lee H

Germ-line mutations in BRCA2 predispose to early-onset cancer. Homozygous mutant mouse, which has Brca2 truncated in exon 11 exhibit paradoxic occurrence of growth retardation and development of thymic lymphomas. However,...
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Immunotherapeutic potential of JL1, a thymocyte surface protein, for leukemia

Kim TJ, Park SH

Tumor-specific antigens for leukemia cells have been sought for the past decades, but none of cell surface markers met sufficient criteria as a 'phenotypic signature'. Here we suggest that...
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