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Estimate of Thrombopoiesis by Flow Cytometric Analysis of Reticulated Platelets in Moderate Thrombocytopenia

Won DI, Suh JS, Lee WK

  • KMID: 2239568
  • Korean J Lab Med.
  • 2003 Jun;23(3):157-163.
BACKGROUND: Measurement of reticulated platelets (RPs) is useful in order to discriminate the causes of thrombocytopenia. In flow cytometric analysis for the percentage of RPs (RPs%), only thiazole orange (TO)...
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Estimate of Thrombopoiesis by Flow Cytometric Analysis of Reticulated Platelets in Patients with Severe Thrombocytopenia

Heo WB, Kim YK, Lee NY, Won DI, Suh JS

  • KMID: 2238989
  • Korean J Lab Med.
  • 2005 Feb;25(1):7-13.
BACKGROUND: Analysis of reticulated platelets (RPs) is useful for discriminating the causes of thrombocytopenia and monitoring the thrombopoiesis. In the patients with severe thrombocytopenia, we evaluated the thrombopoiesis-discriminating ability of...
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Clinical Significance of Platelet Indices in Hematologic Disorders

Lee JH, Moon YS, Kim YG, Han KJ, Shim SI

  • KMID: 2225568
  • Korean J Clin Pathol.
  • 1997 Apr;17(2):201-208.
BACKGROUND: The clinical significance of mean platelet volume (MPV), platelet distribution width (PDW) and megathrombocyte index (MTI) is not clear. METHODS: We examined platelet indices in 900...
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Diagnostic Value of Reticulated Platelet in Thrombocytopenia

Park SH, Kim HM, Lim BK, Shim YH, Lee CH, Kang MS

  • KMID: 1554072
  • J Korean Pediatr Soc.
  • 1997 Jun;40(6):850-856.
PURPOSE: We performed this study to determine the diagnostic significance and useful cut-off value of reticulated platelet, which can be used for discriminating the destructive thrombocytopenia from underproductive thrombocytopenia. METHODS:...
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Factors Related to the Thrombocytosis in Children with Iron Deficiency Anemia

Keun SO, Lee SM, Chung SY, Kang JH, Jeong DC

  • KMID: 2037386
  • Korean J Pediatr Hematol Oncol.
  • 2004 Apr;11(1):32-38.
PURPOSE: We investigated to identify factors related to thrombocytosis and clinical data for thrombopoiesis in children with iron deficiency anemia (IDA). METHODS: We retrospectively analyzed clinical and laboratory data for...
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Clinical Significance of Thrombopoietin Levels in Maintenance Hemodialysis Patients with Thrombocytopenia

Yu JM, Kim JS, Choi JU, Han BG, Choi SO, Lee JI, Uh Y

  • KMID: 2254311
  • Korean J Nephrol.
  • 2004 Jul;23(4):586-592.
BACKGROUND: Thrombopoietin (TPO) is a major cytokine which plays a critical role in the regulation of thrombopoiesis and megakaryopoiesis. Since the kidney is one of the TPO-producing organs, it is...
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Evaluation of Immature Platelet Fraction as a Marker of Platelet Recovery in Prophylactic Platelet Transfusion

Kim H, Kim M, Lim J, Han K, Cho BS, Cho SG, Lee JW, Min WS, Kim Y

  • KMID: 1513826
  • Korean J Blood Transfus.
  • 2007 Aug;18(2):89-96.
BACKGROUND: It has been known that the increase of reticulated platelets indicates the increase of thrombopoiesis in platelet consumptive diseases or the impending platelet recovery in patients with thrombocytopenic conditions....
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Thrombopoietin Level and Bone Marrow Megakaryocyte Colony Formation in Various Diseases with Thrombocytopenia

Cho JS, Choe BK, Cho YJ, Kim HS, Kang CM

  • KMID: 2037432
  • Korean J Pediatr Hematol Oncol.
  • 2000 Oct;7(2):203-211.
PURPOSE: Thrombocytopenia is a serious life threatening consequence in patients with bone marrow failure syndrome. Thrombopoietin (TPO), recently cloned by several groups has been shown to be a key...
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A Case of Cyclic Thrombocytopenia: A Case Report

Lee EH, Kim SG, Suh HS, Shin DG

  • KMID: 2300498
  • Korean J Clin Pathol.
  • 1999 Feb;19(1):15-18.
Cyclic thrombocytopenia is a rare disorder with cyclic change of the platelet counts. Although the pathogenesis of the disorder has not been clarified, recent reports suggest that periodic destruction and/or...
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A Case of Pure Red Cell Anemia Complicated by Antiepileptic Drugs

Kim H, Park SG, Kim SR

  • KMID: 2104467
  • J Korean Pediatr Soc.
  • 1999 Feb;42(2):264-267.
A 12-year-old boy developed pure red cell anemia(PRCA) during a combination therapy of antiepileptic drugs(AEDs) for epilepsy. His complex partial seizure was intractable to monotherapy. During 7 months of treatment,...
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Gene Expression Analysis of Megakaryocytes Derived from Human Umbilical Cord CD34(+) Cells by Thrombopoietin

Kim JA, Kim HL

  • KMID: 1572613
  • Genomics Inform.
  • 2005 Mar;3(1):8-14.
Although much is known about the molecular biology of platelets, the megakaryocytes' (MKs) molecular biology was not understood so well because of their rareness. By the cloning and characterization of...
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Emperipolesis within Megakaryocyte in Hepatic Hemopoiesis

Kim DJ, Yang HC, Ahn JK, Kim SS, Kim KY, Lee WB

  • KMID: 2092693
  • Korean J Anat.
  • 1999 Oct;32(5):593-604.
This study is designed to detect the emperipolesis in megakaryocyte in fetal liver, which is an important organ of hemopoiesis, during rat development, and to compare the activity of erythropoiesis...
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Development and Migration of Megakaryocyte during Hepatic Hemopoiesis in Human Fetuses

Lee WB, Lee CW, Chung BS, Kim BS, Kim DJ, Kim SS, Kim KY

  • KMID: 1559311
  • Korean J Anat.
  • 2002 Aug;35(4):285-296.
Liver tissuses obtained from 5 human fetuses between 11 weeks and 23 weeks of gestation during the high activity of hepatic hemopoiesis were observed with transmission electron microscope using continuous...
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Characterization of CD34 Positive Cord Blood Cells and Ex-vivo Effects of Thrombopoietin on the Expansion of Human Umbilical Cord Blood

Lee WI, Choi YM, Suh JT, Lee HJ

  • KMID: 2300517
  • Korean J Clin Pathol.
  • 1999 Feb;19(1):118-124.
BACKGROUND: Umbilical cord blood (UCB) cells are an alternative source of hemopoietic stem cells for transplantation. However, the use of UCB is limited by the lack of number of hemopoietic...
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