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Inhibition of MUC1 biosynthesis via threonyl-tRNA synthetase suppresses pancreatic cancer cell migration

Jeong SJ, Kim JH, Lim BJ, Yoon I, Song JA, Moon HS, Kim D, Lee DK, Kim S

Mucin1 (MUC1), a heterodimeric oncoprotein, containing tandem repeat structures with a high proportion of threonine, is aberrantly overexpressed in many human cancers including pancreatic cancer. Since the overall survival rate...
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