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Glutathione Reductase and Thioredoxin Reductase: Novel Antioxidant Enzymes from Plasmodium berghei

Kapoor G, Banyal HS

Malaria parasites adapt to the oxidative stress during their erythrocytic stages with the help of vital thioredoxin redox system and glutathione redox system. Glutathione reductase and thioredoxin reductase are important...
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Effects of Thioredoxin on Oxidative Neuronal Cell Injury

Kim H, Kim GH, Lee YS

  • KMID: 2335405
  • J Korean Pediatr Soc.
  • 1999 May;42(5):686-696.
PURPOSE: Thioredoxin is an endogenous antioxidant which directly scavenges reactive oxygen species(ROS) and regenerates oxidatively damaged protein by reducing potential at the redox active disulfide(-Cys-Gly-Pro-Cys-) site. Under oxidative stress, thiredoxin...
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Differential Expression of Peroxiredoxin Isotypes in Cultured Cells from Human and Rat Skin

Ahn EY, Lee JB, Won YH, Lee SC

  • KMID: 2230317
  • Korean J Dermatol.
  • 2000 Nov;38(11):1481-1487.
BACKGROUND: Peroxiredoxin(Prx) is a novel peroxidase family to remove hydrogen peroxide using thioredoxin system, which is consisted of thioredoxin, thioredoxin reductase and NADPH. Several enzymatic antioxidants, such as superoxide dismutase,...
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Expression of Peroxiredoxin I in the Epidermis of Vitiligo

Quan G, Piao MS, Choi JY, Chun JS, Lee JB, Lee SC

  • KMID: 2248128
  • Korean J Dermatol.
  • 2008 Jun;46(6):736-741.
BACKGROUND: Although the pathogenesis of vitiligo isn't fully understood, a recent study demonstrates that oxidative stress plays an important role to induce vitiligo. Peroxiredoxin (Prx) is a novel peroxidase family...
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Expression of Peroxiredoxin and Thioredoxin in Human Lung Cancer and Paired Normal Lung

Kim YS, Park JH, Lee HL, Shim JY, Choi YI, Oh YJ, Shin SS, Choi YH, Park KJ, Park RW, Hwang SC

  • KMID: 2318648
  • Tuberc Respir Dis.
  • 2005 Aug;59(2):142-150.
BACKGROUND: Continuous growth stimulation by various factors, as well as chronic oxidative stress, may co-exist in many solid tumors, such as lung cancer. A new family of antioxidant proteins, the...
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Protective Effects of Peroxiredoxin on Hydrogen Peroxide Induced Oxidative Stress and Apoptosis in Cardiomyocytes

Park KJ, Kim YJ, Kim J, Kim SM, Lee SY, Bae JW, Hwang KK, Kim DW, Cho MC

BACKGROUND AND OBJECTIVES: The redox system is an important anti-oxidative system composed of thioredoxin, thioredoxin reductase, and peroxiredoxin (PRx). The fine details of PRx expression and its protective effects in...
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