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Thunderstorm asthma: potential danger but a unique opportunity

Thien F

No abstract available.
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Measuring and imaging small airways dysfunction in asthma

Thien F

Asthma is a chronic inflammatory disorder of the airways causing typical symptoms, and the diagnosis is supported by evidence of airflow obstruction which is variable, reversible or inducible. However, standard...
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An epidemic of thunderstorm asthma in Melbourne 2016: asthma, rhinitis, and other previous allergies

Rangamuwa , Young AC, Thien F

BACKGROUND: On 21st November 2016, Melbourne experienced an epidemic of ‘thunderstorm asthma.’ Although previously described in the literature, risk factors and natural history remain incompletely understood. OBJECTIVE: Our aim was to...
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Irritable bowel syndrome - An inflammatory disease involving mast cells

Philpott H, Gibson P, Thien F

Irritable bowel syndrome (IBS) is traditionally defined as a functional disorder - that is the presence of symptoms in the absence of demonstrable pathological abnormalities. In recent times, low grade...
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Residential NOâ‚‚ exposure is associated with urgent healthcare use in a thunderstorm asthma cohort

Lai VW, Bowatte G, Knibbs LD, Rangamuwa , Young A, Dharmage S, Thien F

BACKGROUND: There is increasing interest in the role of traffic-related air pollution (TRAP) in allergic airway diseases. Few studies investigate the relationship between TRAP exposure and acute exacerbations of asthma. OBJECTIVE:...
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Continued loss of asthma control following epidemic thunderstorm asthma

Foo CT, Yee EL, Young A, Denton E, Hew M, O'Hehir RE, Radhakrishna N, Matthews S, Conron M, Harun NS, Lachapelle P, Douglass J, Irving L, Lee J, Stevenson , McDonald C, Langton D, Banks C, Thien F

BACKGROUND: Epidemic thunderstorm asthma (ETSA) severely affected Melbourne, Australia in November 2016. There is scant literature on the natural history of individuals affected by ETSA. OBJECTIVE: A multicentre 12-month prospective observational...
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Eosinophilic esophagitis: current understanding and evolving concepts

Philpott H, Kweh B, Thien F

Eosinophilic esophagitis (EoE) is now considered to represent a form of food allergy and this is demonstrated by a response to elimination diet in many patients. A critical additional factor...
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Oral antiplatelet agent hypersensitivity and cross-reactivity managed by successful desensitisation

Chin N, Rangamuwa , Mariasoosai R, Carnes J, Thien F

Oral platelet aggregation inhibitors are widely used for the treatment and prevention of cardiovascular diseases, including coronary stent thrombosis. Premature discontinuation following percutaneous coronary intervention would pose a grave risk...
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Asia Pacific Association of Allergy Asthma and Clinical Immunology White Paper 2020 on climate change, air pollution, and biodiversity in Asia-Pacific and impact on allergic diseases

Pawankar R, Wang JY, Wang IJ, Thien F, Chang YS, Latiff AH, Fujisawa T, Zhang L, Thong BY, Chatchatee P, Leung TF, Kamchaisatian W, Rengganis , Yoon HJ, Munkhbayarlakh S, Recto MT, Neo AG, Le Pham D, Lan LT, Davies JM, Oh JW

Air pollution, climate change, and reduced biodiversity are major threats to human health with detrimental effects on a variety of chronic noncommunicable diseases in particular respiratory and cardiovascular diseases. The...
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Drug hypersensitivity reactions in Asia: regional issues and challenges

Thong BY, Lucas M, Kang HR, Chang YS, Li PH, Tang MM, Yun J, Fok JS, Kim BK, Nagao M, Rengganis , Tsai YG, Chung WH, Yamaguchi , Rerkpattanapipat T, Kamchaisatian W, Leung TF, Yoon HJ, Zhang L, Latiff AH, Fujisawa T, Thien F, Castells M, Demoly P, Wang JY, Pawankar R

There are geographical, regional, and ethnic differences in the phenotypes and endotypes of patients with drug hypersensitivity reactions (DHRs) in different parts of the world. In Asia, aspects of drug...
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