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Autophagy: a lysosomal degradation process for cellular homeostasis and its relationship with oral squamous cell carcinoma

Jung J, Kim J, Kim JH

Autophagy is an evolutionarily well-conserved cellular homeostasis program that responds to various cellular stresses and degrades unnecessary or harmful intracellular materials in lysosomes. Accumulating evidence has shown that autophagy dysfunction...
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Phosphoproteomic analysis identifies activated MET-axis PI3K/AKT and MAPK/ERK in lapatinib-resistant cancer cell line

Lee YY, Kim HP, Kang MJ, Cho BK, Han SW, Kim TY, Yi EC

  • KMID: 2154283
  • Exp Mol Med.
  • 2013 Nov;45(11):e64.
Lapatinib, a dual inhibitor of epidermal growth factor receptor (EGFR) and human epidermal growth factor receptor 2 (HER2) tyrosine kinases, has shown promising results as a growth inhibitor of HER2-positive...
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