- Efficacy and Tolerability of Theobromine in Patients with Upper Airway Cough Syndrome: A Multicenter, Double-Blind, Randomized, Active Drug Comparative Study
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Kim YH, Kim SW, Kim CH, Kim KS, Kim TH, Lee HM, Cho JH
- KMID: 2297595
- J Rhinol.
- 2011 Nov;18(2):128-134.
OBJECTIVES: The objective of this study is to evaluate the efficacy and tolerability of theobromine in patients with upper airway cough syndrome compared to those of levocloperastine. MATERIALS AND METHOD: This... -
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- Pharmacokinetic Interaction of Chrysin with Caffeine in Rats
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Noh K, Oh DG, Nepal MR, Jeong KS, Choi Y, Kang MJ, Kang W, Jeong HG, Jeong TC
- KMID: 2351695
- Biomol Ther.
- 2016 Jul;24(4):446-452.
- doi: 10.4062/biomolther.2015.197
Pharmacokinetic interaction of chrysin, a flavone present in honey, propolis and herbs, with caffeine was investigated in male Sprague-Dawley rats. Because chrysin inhibited CYP1A-selective ethoxyresorufin O-deethylase and methoxyresorufin O-demethylase activities... -
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- Assessment of flavin-containing monooxygenase (FMO) activity by determining urinary ratio of theobromine and caffeine in a Korean population after drinking a cup of coffee
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Chung WG, Kang JH, Roh HK, Lee KH, Park CS, Cha YN
- KMID: 1554144
- Korean J Physiol Pharmacol.
- 1999 Apr;3(2):207-213.
To examine individual variation in drug metabolism catalyzed by flavin-containing monooxygenase (FMO), 179 Korean volunteers' urinary molar concentration ratio of theobromine (TB) and caffeine (CA) was determined. Their urine was collected for 1... -
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- Effects of Baicalin on Oral Pharmacokinetics of Caffeine in Rats
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Noh K, Nepal MR, Jeong KS, Kim SA, Um YJ, Seo CS, Kang MJ, Park PH, Kang W, Jeong HG, Jeong TC
- KMID: 2380355
- Biomol Ther.
- 2015 Mar;23(2):201-206.
- doi: 10.4062/biomolther.2014.134
Scutellaria baicalensis is one of the most widely used herbal medicines in East Asia. Because baicalein and baicalin are major components of this herb, it is important to understand the... -
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