- Immunohistochemical detection of GluA1 subunit of AMPA receptor in the rat nucleus accumbens following cocaine exposure
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Cai WT, Han J, Kim WY, Kim JH
- KMID: 2509657
- Korean J Physiol Pharmacol.
- 2021 Jan;25(1):79-85.
- doi: 10.4196/kjpp.2021.25.1.79
α-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid (AMPA) receptors are differentially regulated in the nucleus accumbens (NAcc) of the brain after cocaine exposure. However, these results are supported only by biochemical and electrophysiological methods,... -
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- Ovariectomy, but not orchiectomy, exacerbates metabolic syndrome after maternal high-fructose intake in adult offspring
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Kim M, Kim I
- KMID: 2509653
- Korean J Physiol Pharmacol.
- 2021 Jan;25(1):39-49.
- doi: 10.4196/kjpp.2021.25.1.39
High fructose diet is associated with the global metabolic syndrome (MtS) pandemic. MtS develops in early life, depending on prenatal and postnatal nutritional status. We hypothesized that ovariectomy increases the... -
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- Genetic approaches toward understanding the individual variation in cardiac structure, function and responses to exercise training
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Kim M, Kim SK
- KMID: 2509650
- Korean J Physiol Pharmacol.
- 2021 Jan;25(1):1-14.
- doi: 10.4196/kjpp.2021.25.1.1
Cardiovascular disease (CVD) accounts for approximately 30% of all deaths worldwide and its prevalence is constantly increasing despite advancements in medical treatments. Cardiac remodeling and dysfunction are independent risk factors... -
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- Whitening effect of novel peptide mixture by regulating melanosome biogenesis, transfer and degradation
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Lee EJ, Kim J, Jeong MK, Lee YM, Chung YJ, Kim EM
- KMID: 2509651
- Korean J Physiol Pharmacol.
- 2021 Jan;25(1):15-26.
- doi: 10.4196/kjpp.2021.25.1.15
Peptides are short chain of amino acids linked by peptide bonds. They are widely used as effective and biocompatible active ingredients in cosmetic industry. In this study, we developed novel... -
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- Nootkatol prevents ultraviolet radiation-induced photoaging via ORAI1 and TRPV1 inhibition in melanocytes and keratinocytes
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Woo JH, Nam DY, Kim HJ, Hong PTL, Kim WK, Nam JH
- KMID: 2509658
- Korean J Physiol Pharmacol.
- 2021 Jan;25(1):87-94.
- doi: 10.4196/kjpp.2021.25.1.87
Skin photoaging occurs due to chronic exposure to solar ultraviolet radiation (UV), the main factor contributing to extrinsic skin aging. Clinical signs of photoaging include the formation of deep, coarse... -
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- Ref-1 protects against FeCl3 -induced thrombosis and tissue factor expression via the GSK3β–NF-κB pathway
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Lee I, Nagar H, Kim S, Choi Sj, Piao S, Ahn M, Jeon BH, Oh SH, Kang SK, Kim CS
- KMID: 2509655
- Korean J Physiol Pharmacol.
- 2021 Jan;25(1):59-68.
- doi: 10.4196/kjpp.2021.25.1.59
Arterial thrombosis and its associated diseases are considered to constitute a major healthcare problem. Arterial thrombosis, defined as blood clot formation in an artery that interrupts blood circulation, is associated... -
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- The effect of adenosine triphosphate on propofol-induced myopathy in rats: a biochemical and histopathological evaluation
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Erdem KTO, Bedir Z, Ates I, Kuyrukluyildiz U, Coban TA, Yazici GN, Arslan YK, Suleyman Z, Suleyman H
- KMID: 2509656
- Korean J Physiol Pharmacol.
- 2021 Jan;25(1):69-77.
- doi: 10.4196/kjpp.2021.25.1.69
Propofol infusion syndrome characterized by rhabdomyolysis, metabolic acidosis, kidney, and heart failure has been reported in long-term propofol use for sedation. It has been reported that intracellular adenosine triphosphate (ATP)... -
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- Oxidative stress-induced aberrant G9a activation disturbs RE-1-containing neuron-specific genes expression, leading to degeneration in human SH-SY5Y neuroblastoma cells
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Kim HT, Ohn T, Jeong SG, Song A, Jang CH, Cho GW
- KMID: 2509654
- Korean J Physiol Pharmacol.
- 2021 Jan;25(1):51-58.
- doi: 10.4196/kjpp.2021.25.1.51
Oxidative stress-induced neurodegeneration is one of several etiologies underlying neurodegenerative disease. In the present study, we investigated the functional role of histone methyltransferase G9a in oxidative stress-induced degeneration in human... -
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- Gamma-aminobutyric acid-salt attenuated high cholesterol/high salt diet induced hypertension in mice
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Son M, Oh S, Lee HS, Choi J, Lee BJ, Park JH, Park CH, Son KH, Byun K
- KMID: 2509652
- Korean J Physiol Pharmacol.
- 2021 Jan;25(1):27-38.
- doi: 10.4196/kjpp.2021.25.1.27
Excessive salt intake induces hypertension, but several gamma-aminobutyric acid (GABA) supplements have been shown to reduce blood pressure. GABAsalt, a fermented salt by L. brevis BJ20 containing GABA was prepared... -
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