- Multiple Residues in the P-Region and M2 of Murine Kir 2.1 Regulate Blockage by External Ba2+
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Lee YM, Thompson G, Ashmole I, Leyland M, So I, Stanfield
- KMID: 2285373
- Korean J Physiol Pharmacol.
- 2009 Feb;13(1):61-70.
- doi: 10.4196/kjpp.2009.13.1.61
We have examined the effects of certain mutations of the selectivity filter and of the membrane helix M2 on Ba2+ blockage of the inward rectifier potassium channel, Kir 2.1. We... -
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- Quantitative Structure Activity Relationship between Diazabicyclo[4.2.0]octanes Derivatives and Nicotinic Acetylcholine Receptor Agonists
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Kim EA, Jung KC, Sohn UD, Im C
- KMID: 2285372
- Korean J Physiol Pharmacol.
- 2009 Feb;13(1):55-59.
- doi: 10.4196/kjpp.2009.13.1.55
Three dimensional quantitative structure activity relationship between diazabicyclo[4.2.0]octanes and nicotinic acetylcholine receptor (h alpha4beta2 and h alpha3beta4) agonists was studied using comparative molecular field analysis (CoMFA) and comparative molecular similarity... -
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- Mechanisms of Selective Antimicrobial Activity of Gaegurin 4
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Kim H, Lee BJ, Lee MH, Hong SG, Ryu PD
- KMID: 2285370
- Korean J Physiol Pharmacol.
- 2009 Feb;13(1):39-47.
- doi: 10.4196/kjpp.2009.13.1.39
Gaegurin 4 (GGN4), an antimicrobial peptide isolated from a Korean frog, is five times more potent against Gram-positive than Gram-negative bacteria, but has little hemolytic activity. To understand the mechanism... -
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- P2 Receptor-mediated Inhibition of Vasopressin-stimulated Fluid Transport and cAMP Responses in AQP2-transfected MDCK Cells
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Kim YH, Choi YJ, Bae HR, Woo JS
- KMID: 2285365
- Korean J Physiol Pharmacol.
- 2009 Feb;13(1):9-14.
- doi: 10.4196/kjpp.2009.13.1.9
We cultured canine kidney (MDCK) cells stably expressing aquaporin-2 (AQP2) on collagen-coated permeable membrane filters and examined the effect of extracellular ATP on arginine vasopressin (AVP)-stimulated fluid transport and cAMP... -
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- Changes of Atrial Natriuretic Peptide System in Rats with Puromycin Aminonucleoside-Induced Nephrotic Syndrome
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Bae EH, Lee JU, Ma SK, Kim SW
- KMID: 2285364
- Korean J Physiol Pharmacol.
- 2009 Feb;13(1):1-7.
- doi: 10.4196/kjpp.2009.13.1.1
Sodium retention is a hallmark of nephrotic syndrome. We investigated whether sodium retention is associated with changes of natriuretic peptide system at different stages (i.e., a sodium retaining stage and... -
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- Oxidized Low-density Lipoprotein- and Lysophosphatidylcholine-induced Ca2+ Mobilization in Human Endothelial Cells
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Kim MY, Liang GH, Kim JA, Choi SS, Choi S, Suh SH
- KMID: 2285368
- Korean J Physiol Pharmacol.
- 2009 Feb;13(1):27-32.
- doi: 10.4196/kjpp.2009.13.1.27
The effects of oxidized low-density lipoprotein (OxLDL) and its major lipid constituent lysophosphatidylcholine (LPC) on Ca2+ entry were investigated in cultured human umbilical endothelial cells (HUVECs) using fura-2 fluorescence and... -
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- Effects of AIF on Knee Osteoarthritis Patients: Double-blind, Randomized Placebo-controlled Study
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Park SH, Kim SK, Shin IH, Kim HG, Choe JY
- KMID: 2285369
- Korean J Physiol Pharmacol.
- 2009 Feb;13(1):33-37.
- doi: 10.4196/kjpp.2009.13.1.33
Anti-inflammatory factor (AIF) is a water soluble extract of three herbs, Panax notoginseng (Burk.) F. H. Chen, Rehmannia glutinosa Libosch and Eleutherococcus senticosus. The present study aimed to investigate the... -
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- Antifungal and Anticancer Activities of a Protein from the Mushroom Cordyceps militaris
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Park BT, Na KH, Jung EC, Park JW, Kim HH
- KMID: 2285371
- Korean J Physiol Pharmacol.
- 2009 Feb;13(1):49-54.
- doi: 10.4196/kjpp.2009.13.1.49
The mushroom Cordyceps militaris has been used for a long time in eastern Asia as a nutraceutical and in traditional Chinese medicine as a treatment for cancer patients. In the... -
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- Alterations in Membrane Transport Function and Cell Viability Induced by ATP Depletion in Primary Cultured Rabbit Renal Proximal Tubular Cells
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Lee SJ, Kwon CH, Kim YK
- KMID: 2285366
- Korean J Physiol Pharmacol.
- 2009 Feb;13(1):15-22.
- doi: 10.4196/kjpp.2009.13.1.15
This study was undertaken to elucidate the underlying mechanisms of ATP depletion-induced membrane transport dysfunction and cell death in renal proximal tubular cells. ATP depletion was induced by incubating cells... -
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- The Effect of Extracellular Glutamate Release on Repetitive Transient Ischemic Injury in Global Ischemia Model
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Lee GJ, Choi SK, Eo YH, Kang SW, Choi S, Park JH, Lim JE, Hong KW, Jin HS, Oh BS, Park HK
- KMID: 2285367
- Korean J Physiol Pharmacol.
- 2009 Feb;13(1):23-26.
- doi: 10.4196/kjpp.2009.13.1.23
During operations, neurosurgeons usually perform multiple temporary occlusions of parental artery, possibly resulting in the neuronal damage. It is generally thought that neuronal damage by cerebral ischemia is associated with... -
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