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We elucidated the effects of various components of ischemic medium on the outcome of simulated ischemia-reperfusion injury. Hypoxia for up to 12 hours induced neither apoptotic bodies nor LDH release....
Cisplatin treatment increases the excretion of inorganic phosphate in vivo. However, the mechanism by which cisplatin reduces phosphate uptake through renal proximal tubular cells has not yet been elucidated. We...
Adenosine has been reported to provide cytoprotection in the central nervous systems as well as myocardium by activating cell surface adenosine receptors. However, the exact target and mechanism of its...
Kang YJ, Moon HS, Kim HJ, Seo HG, Lee JH, Chang KC
KMID: 1512909
Korean J Physiol Pharmacol.
2007 Apr;11(2):65-70.
Chinese herb medicines have traditionally been used to treat or alleviate the symptom of various diseases. The rationale for use of certain herbs to certain disorder is now getting unveiled...
Thu VT, Cuong DV, Kim N, Youm JB, Warda M, Park WS, Ko JH, Kim E, Han J
KMID: 1512908
Korean J Physiol Pharmacol.
2007 Apr;11(2):57-64.
Ischemic preconditioning (IPC) is known to protect the heart against ischemia/reperfusion (IR)-induced injuries, and regional differences in the mitochondrial antioxidant state during IR or IPC may promote the death or...