- Effects of Phenylephrine on the Excitability of Medial Vestibular Nuclear Neurons in Rats
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Jeong HS, Huh HR, Jang MJ, Hong SH, Jang S, Park J, Lee SH, Kim JH, Park JS
- KMID: 2285323
- Korean J Physiol Pharmacol.
- 2006 Jun;10(3):131-135.
Coeruleo-vestibular pathway which connects locus coeruleus and vestibular nuclei is noradrenergic. This study was designed to elucidate the effects of phenylephrine on the spontaneous activity of acutely isolated medial vestibular... -
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- Neuroprotective Effects of Lithium on NMDA-induced Excitotoxicity in Mouse Cerebrum
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Kwon GY, Kim SK
- KMID: 2285321
- Korean J Physiol Pharmacol.
- 2006 Jun;10(3):111-121.
Neuroprotective properties of lithium were evaluated by using in vivo NMDA excitotoxicity model. Systemic injection of NMDA to young mice induced neuronal apoptosis mediated by both TNFR-1 and Fas ligand,... -
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- Changes of Hemodynamics and Renal Function due to Acute Cadmium Exposure in Rats
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Kim JJ, Kim YK
- KMID: 2285324
- Korean J Physiol Pharmacol.
- 2006 Jun;10(3):137-141.
The systolic and diastolic pressures in anesthetized Sprague-Dawley male rats were greatly decreased after single-dose of Cd treatment without significant changes in heart rate. There was a fluid-shift into the... -
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- Nitric Oxide Donor, NOR-3, Increased Expression of Cyclooxygenase-2, but not of Cyclooxygenase-1 in Cultured VSMC
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Lee DH, Park JE, Kang YJ, Lee KY, Choi HC
- KMID: 2285328
- Korean J Physiol Pharmacol.
- 2006 Jun;10(3):161-165.
NO and cyclooxygenase-2 (COX-2) are contributes to vascular inflammation induced by various stimulation. The mechanism, which explains a linkage between NO and COX-2, could be of importance in promoting pathophysiological... -
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- Carthamus tinctorius L. Increases BMP-2 Gene Expression during Bone Fracture Healing in Rats
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Lee KH, Sohn OJ, Ahn JC, Kim YW, Park SY, Kim JY
- KMID: 2285325
- Korean J Physiol Pharmacol.
- 2006 Jun;10(3):143-147.
Carthamus tinctorius L.is known to improve fracture healing, and bone morphogenetic proteins (BMPs) are associated with the formation and healing process of bone. BMP-2 and BMP-7 are two of the... -
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- Estrogen Pretreatment of Organotypic Hippocampal Slices Protects Neurons against Oxygen-Glucose Deprivation with Akt Activation
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Park EM, Hong S, Lee KE
- KMID: 2285322
- Korean J Physiol Pharmacol.
- 2006 Jun;10(3):123-129.
In several experimental models, estrogens protect neurons against ischemic insults. However, the recent clinical studies of hormone replacement showed negative results to prevent stroke. Therefore, optimal models to study estrogen... -
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- p66shc Adaptor Protein Suppresses the Activation of Endothelial Nitric Oxide Synthase in Mouse Embryonic Fibroblasts
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Lee SK, Kim YS, Kim CS, Son SJ, Yoo DG, Lee KH, Lee SD, Park JB, Jeon BH
- KMID: 2285327
- Korean J Physiol Pharmacol.
- 2006 Jun;10(3):155-159.
Among the Shc proteins, p66shc is known to be related to oxidative stress responses and regulation of the production of reactive oxygen species (ROS). The present study was undertaken to... -
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- Effects of Phosphodiesterase 5 Inhibition with Sildenafil on Atrial Contractile and Secretory Function
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Quan HX, Kim SY, Jin XS, Park JK, Kim SZ, Cho KW
- KMID: 2285326
- Korean J Physiol Pharmacol.
- 2006 Jun;10(3):149-154.
Selective inhibition of phosphodiesterase (PDE) 5 opened a new therapeutic approach for cardiovascular disorders. Therefore, the effect of PDE5 inhibition on the cardiac function should thoroughly be defined. The purpose... -
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