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Role of Stretch-Activated Channels in Stretch-Induced Changes of Electrical Activity in Rat Atrial Myocytes

Youm JB, Jo SH, Leem CH, Ho WK, Earm YE

  • KMID: 1517035
  • Korean J Physiol Pharmacol.
  • 2004 Feb;8(1):33-41.
We developed a cardiac cell model to explain the phenomenon of mechano-electric feedback (MEF), based on the experimental data with rat atrial myocytes. It incorporated the activity of ion channels,...
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Pharmacokinetics of Dehydroevodiamine Following Intravenous Administration in Rats

Kim SY, Moon CS, Choi YS, Lee SB

  • KMID: 1517039
  • Korean J Physiol Pharmacol.
  • 2004 Feb;8(1):65-67.
Dehydroevodiamine (DHED) is one of the bioactive components of the Chinese herbal medicine Wu-chu-yu-tang that has been shown to produce various pharmacological effects. In the present study, we investigated the...
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Anti-Apoptotic Effect of Rheum undulatum Water Extract in Pancreatic beta-cell Line, HIT-T15

Yoon SH, Hong MS, Chung JH, Chung SH

  • KMID: 1517037
  • Korean J Physiol Pharmacol.
  • 2004 Feb;8(1):51-55.
Sopungsungi-won has been used as a traditional medicine for diabetes and it has been proved to be a potential remedy for type 2 diabetes mellitus. We previously reported that water...
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Decreased Expression of PTEN in Olfactory Bulb of Rat Pub after Naris Closure

Cho J, Lee SH, Lee GH, Chun W, Park YT, Lim SY, Kim SS

  • KMID: 1517032
  • Korean J Physiol Pharmacol.
  • 2004 Feb;8(1):17-20.
PTEN (phosphatase and tensin homolog) is a dual specific phosphatase antagonizing phosphoinositide 3-kinase activity, and has first been cloned as a tumor suppressor for glioma. Although the role of PTEN...
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Economical Sweating Function in Africans: Quantitative Sudomotor Axon Reflex Test

Lee JB, Bae JS, Choi JH, Ham JH, Min YK, Yang HM, Kazuhiro S, Matsumoto

  • KMID: 1517033
  • Korean J Physiol Pharmacol.
  • 2004 Feb;8(1):21-25.
People in tropics have the ability to tolerate heat by residential permanence in the tropics. Previously, we have shown that African and Thai subjects who lived for whole their lives...
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Postischemic Treatment with Aminoguanidine Inhibits Peroxynitrite Production in the Rat Hippocampus Following Transient Forebrain Ischemia

Choi YS, Yoon YH, Lee JE, Cho KO, Kim SY, Lee SB

  • KMID: 1517030
  • Korean J Physiol Pharmacol.
  • 2004 Feb;8(1):1-5.
Transient forebrain ischemia results in the delayed neuronal death in the CA1 area of the hippocampus. The present study was performed to determine effects of aminoguanidine, a selective iNOS inhibitor,...
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Efffects of Fluoxetine on ATP-induced Calcium Signaling in PC12 Cells

Lee YM, Kim HJ, Hong SH, Kim MJ, Min DS, Rhie DJ, Kim MS, Jo YH, Hahn SJ, Yoon SH

  • KMID: 1517038
  • Korean J Physiol Pharmacol.
  • 2004 Feb;8(1):57-63.
Fluoxetine, a widely used anti-depressant compound, has several additional effects, including blockade of voltage-gated ion channels. We examined whether fluoxetine affects ATP-induced calcium signaling in PC12 cells by using fura-2-based...
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Role of STAT3-Interacting Protein (STIP1) in delta12-Prostaglandin J2-Induced Cell Death

Kim SM, Lee S, Kwak HJ, Kim BE, Kim DJ, Kim IK, Jeong SW

  • KMID: 1517034
  • Korean J Physiol Pharmacol.
  • 2004 Feb;8(1):27-31.
delta12-Prostaglandin J2 (delta12-PGJ2) is one of cyclopentenone prostaglandins. The delta12-PGJ2 is known to induce apoptosis of tumor cells, however, it's action mechanism is not clear. It has recently been reported...
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Effect of Amrinone, a Selective Inhibitor of Phosphodiesterase III, on PMNs-induced Cardiac Dysfunction in Ischemia/reperfusion

Oh BK, Kim HK, Choi SR, Song JH, Park ES, Choi BS, Park JD, Shin YK

  • KMID: 1517036
  • Korean J Physiol Pharmacol.
  • 2004 Feb;8(1):43-50.
Ischemia followed by reperfusion in the presence of polymorphonuclear leukocytes (PMNs) results in a marked cardiac contractile dysfunction. Amrinone, a specific inhibitor of phosphodiesterase 3, has an antioxidant activity against...
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Nitric Oxide (NO) Inhibites the Neuronal Activities in the Rat Nucleus Tractus Solitarius

Kim MW, Park MS, Ryu SY, Jung JY, Jeong YJ, Kim SH, Kim MS, Kim WJ

  • KMID: 1517031
  • Korean J Physiol Pharmacol.
  • 2004 Feb;8(1):7-15.
Nitric oxide (NO) system has been implicated in a wide range of physiological functions in the nervous system. However, the roleof NO in regulating the neural activity in the gustatory...
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