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A Simple and Accurate Method for Determining Antioxidative Activity

Bae JW, Lee MH

  • KMID: 1517044
  • Korean J Physiol Pharmacol.
  • 2003 Oct;7(5):275-278.
Antioxidative activity is an important factor in inhibiting oxidative stress. The usual methods for determining antioxidative activity are time-consuming and cumbersome. They are also indirect processes that use biological material...
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The Substates with Mutants That Negatively Charged Aspartate in Position 172 Was Replaced with Positive Charge in Murine Inward Rectifier Potassium Channel (Murine Kir2.1)

So I, Ashmole I, Stanfield

  • KMID: 1517043
  • Korean J Physiol Pharmacol.
  • 2003 Oct;7(5):267-273.
We have investigated the effect on inducing substate (s) of positively charged residues replaced in position 172 of the second transmembrane domain in murine inward rectifier potassium channels, formed by...
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Merlin Represses Ras-Induced Cyclin D1 Transcription through the Cyclic AMP-Responsive Element

Kwak NJ, Kim H, Choi BH, Kim YH, Rha HK, Lee KH

  • KMID: 1517047
  • Korean J Physiol Pharmacol.
  • 2003 Oct;7(5):289-293.
Mutations in the NF2 tumor suppressor gene cause neurofibromatosis type 2, an autosomal dominant inherited syndrome predisposed to the multiple tumors of the nervous system. Merlin, the NF2 gene product...
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Antagonists of NMDA Receptor, Calcium Channel and Protein Kinase C Potentiate Inhibitory Action of Morphine on Responses of Rat Dorsal Horn Neuron

Shin HK, Kim YS, Jun JH, Lee SE, Kim JH

  • KMID: 1517040
  • Korean J Physiol Pharmacol.
  • 2003 Oct;7(5):251-254.
he present study was designed to examine whether the co-application of morphine with Ca2+ channel antagonist (Mn2+, verapamil), N-methyl-D-aspartate (NMDA) receptor antagonist (2-amino-5-phosphonopentanoic acid[AP5], Mg2+) or protein kinase C inhibitor...
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Prevention of Diabetes Using Adenoviral Mediated Hepatocyte Growth Factor Gene Transfer in Mice

Lee HJ, Kim HJ, Roh MS, Lee JI, Lee SW, Jung DS, Kim DK, Park MK

  • KMID: 1517042
  • Korean J Physiol Pharmacol.
  • 2003 Oct;7(5):261-266.
Type 1 diabetes is an organ-specific autoimmune disease caused by the cytotoxic T cells-mediated destruction of the insulin-producing beta cells in the Langerhans pancreatic islets. Hepatocyte growth factor (HGF) is...
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Inhibitory Effect of Esculetin on the Inducuble Nitric Oxide Synthase Expression in TNF-stimulated 3T3-L1 Adipocytes

Yang JY

  • KMID: 1517046
  • Korean J Physiol Pharmacol.
  • 2003 Oct;7(5):283-287.
While nitric oxide (NO) produced by inducible nitric oxide synthase (iNOS) is beneficial for host survival, it is also detrimental to the host. Thus, regulation of iNOS gene expression may...
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CD40 Activation Protects Dendritic Cells from Anticancer Drug-Induced Apoptosis

Jun JY, Joo HG

  • KMID: 1517041
  • Korean J Physiol Pharmacol.
  • 2003 Oct;7(5):255-260.
Dendritic cells (DCs) play a critical role in various immune responses involving CD4 T cells and have been used to generate anti-tumor immunity. Chemotherapy induces severe side effects including immunosuppression...
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Expression Profiles of Immune-related Genes in Fluoxetine-treated Human Mononuclear Cells by cDNA Microarray

Lee HJ, Jin SY, Hong MS, Li GZ, Kim JW, Kim BS, Chung JH

  • KMID: 1517045
  • Korean J Physiol Pharmacol.
  • 2003 Oct;7(5):279-282.
To investigate the effect of fluoxetine, one of selective serotonin reuptake inhibitors (SSRIs), on the immune system, human peripheral blood mononuclear cells (PBMC) were treated with fluoxetine (10 7 M)...
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